Duffield AS - Search Results

1

NPMc+ cooperates with Flt3/ITD mutations to cause acute leukemia recapitulating human disease.

Rau R, Magoon D, Greenblatt S, Li L, Annesley C, Duffield AS, Huso D, McIntyre E, Clohessy JG, Reschke M, Pandolfi PP, Small D, Brown P. Rau R, et al. Among authors: duffield as. Exp Hematol. 2014 Feb;42(2):101-13.e5. doi: 10.1016/j.exphem.2013.10.005. Epub 2013 Oct 29. Exp Hematol. 2014. PMID: 24184354 Free PMC article.

2

Knock-in of a FLT3/ITD mutation cooperates with a NUP98-HOXD13 fusion to generate acute myeloid leukemia in a mouse model.

Greenblatt S, Li L, Slape C, Nguyen B, Novak R, Duffield A, Huso D, Desiderio S, Borowitz MJ, Aplan P, Small D. Greenblatt S, et al. Blood. 2012 Mar 22;119(12):2883-94. doi: 10.1182/blood-2011-10-382283. Epub 2012 Feb 8. Blood. 2012. PMID: 22323452 Free PMC article.

3

Clinical and pathologic features of secondary acute promyelocytic leukemia.

Duffield AS, Aoki J, Levis M, Cowan K, Gocke CD, Burns KH, Borowitz MJ, Vuica-Ross M. Duffield AS, et al. Am J Clin Pathol. 2012 Mar;137(3):395-402. doi: 10.1309/AJCPE0MV0YTWLUUE. Am J Clin Pathol. 2012. PMID: 22338051 Free PMC article.

4

Flow cytometric findings in hemophagocytic lymphohistiocytosis.

McCall CM, Mudali S, Arceci RJ, Small D, Fuller S, Gocke CD, Vuica-Ross M, Burns KH, Borowitz MJ, Duffield AS. McCall CM, et al. Among authors: duffield as. Am J Clin Pathol. 2012 May;137(5):786-94. doi: 10.1309/AJCPP40MEXWYRLPN. Am J Clin Pathol. 2012. PMID: 22523218 Free PMC article.

5

Effect of FLT3 ligand on survival and disease phenotype in murine models harboring a FLT3 internal tandem duplication mutation.

Bailey EJ, Duffield AS, Greenblatt SM, Aplan PD, Small D. Bailey EJ, et al. Among authors: duffield as. Comp Med. 2013 Jun;63(3):218-26. Comp Med. 2013. PMID: 23759524 Free PMC article.

6

Targeted pathologic evaluation of bone marrow donors identifies previously undiagnosed marrow abnormalities.

Tilson MP, Jones RJ, Sexauer A, Griffin CA, Morsberger LA, Batista DA, Small D, Burns KH, Gocke CD, Vuica-Ross M, Borowitz MJ, Duffield AS. Tilson MP, et al. Among authors: duffield as. Biol Blood Marrow Transplant. 2013 Aug;19(8):1254-9. doi: 10.1016/j.bbmt.2013.05.022. Epub 2013 Jun 13. Biol Blood Marrow Transplant. 2013. PMID: 23769818 Free PMC article.

7

FLT3/D835Y mutation knock-in mice display less aggressive disease compared with FLT3/internal tandem duplication (ITD) mice.

Bailey E, Li L, Duffield AS, Ma HS, Huso DL, Small D. Bailey E, et al. Among authors: duffield as. Proc Natl Acad Sci U S A. 2013 Dec 24;110(52):21113-8. doi: 10.1073/pnas.1310559110. Epub 2013 Nov 19. Proc Natl Acad Sci U S A. 2013. PMID: 24255108 Free PMC article.

8

TTT-3002 is a novel FLT3 tyrosine kinase inhibitor with activity against FLT3-associated leukemias in vitro and in vivo.

Ma H, Nguyen B, Li L, Greenblatt S, Williams A, Zhao M, Levis M, Rudek M, Duffield A, Small D. Ma H, et al. Blood. 2014 Mar 6;123(10):1525-34. doi: 10.1182/blood-2013-08-523035. Epub 2014 Jan 9. Blood. 2014. PMID: 24408321 Free PMC article.

9

FLT3 kinase inhibitor TTT-3002 overcomes both activating and drug resistance mutations in FLT3 in acute myeloid leukemia.

Ma HS, Nguyen B, Duffield AS, Li L, Galanis A, Williams AB, Brown PA, Levis MJ, Leahy DJ, Small D. Ma HS, et al. Among authors: duffield as. Cancer Res. 2014 Sep 15;74(18):5206-17. doi: 10.1158/0008-5472.CAN-14-1028. Epub 2014 Jul 24. Cancer Res. 2014. PMID: 25060518 Free PMC article.

10

All-trans retinoic acid synergizes with FLT3 inhibition to eliminate FLT3/ITD+ leukemia stem cells in vitro and in vivo.

Ma HS, Greenblatt SM, Shirley CM, Duffield AS, Bruner JK, Li L, Nguyen B, Jung E, Aplan PD, Ghiaur G, Jones RJ, Small D. Ma HS, et al. Among authors: duffield as. Blood. 2016 Jun 9;127(23):2867-78. doi: 10.1182/blood-2015-05-646786. Epub 2016 Apr 21. Blood. 2016. PMID: 27103744 Free PMC article.

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