Fischer PM - Search Results

1

Synthesis, structure-activity relationship and biological evaluation of 2,4,5-trisubstituted pyrimidine CDK inhibitors as potential anti-tumour agents.

Shao H, Shi S, Foley DW, Lam F, Abbas AY, Liu X, Huang S, Jiang X, Baharin N, Fischer PM, Wang S. Shao H, et al. Among authors: fischer pm. Eur J Med Chem. 2013;70:447-55. doi: 10.1016/j.ejmech.2013.08.052. Epub 2013 Sep 15. Eur J Med Chem. 2013. PMID: 24185375

2

Inhibitors of cyclin-dependent kinases as anti-cancer therapeutics.

Fischer PM, Lane DP. Fischer PM, et al. Curr Med Chem. 2000 Dec;7(12):1213-45. doi: 10.2174/0929867003374048. Curr Med Chem. 2000. PMID: 11032968

3

Peptide inhibitors of CDK2-cyclin A that target the cyclin recruitment-site: structural variants of the C-terminal Phe.

Atkinson GE, Cowan A, McInnes C, Zheleva DI, Fischer PM, Chan WC. Atkinson GE, et al. Among authors: fischer pm. Bioorg Med Chem Lett. 2002 Sep 16;12(18):2501-5. doi: 10.1016/s0960-894x(02)00508-5. Bioorg Med Chem Lett. 2002. PMID: 12182847

4

New lupane derived compounds with pro-apoptotic activity in cancer cells: synthesis and structure-activity relationships.

Sarek J, Klinot J, Dzubák P, Klinotová E, Nosková V, Krecek V, Korínková G, Thomson JO, Janost'áková A, Wang S, Parsons S, Fischer PM, Zhelev NZ, Hajdúch M. Sarek J, et al. Among authors: fischer pm. J Med Chem. 2003 Dec 4;46(25):5402-15. doi: 10.1021/jm020854p. J Med Chem. 2003. PMID: 14640549

5

2-Anilino-4-(thiazol-5-yl)pyrimidine CDK inhibitors: synthesis, SAR analysis, X-ray crystallography, and biological activity.

Wang S, Meades C, Wood G, Osnowski A, Anderson S, Yuill R, Thomas M, Mezna M, Jackson W, Midgley C, Griffiths G, Fleming I, Green S, McNae I, Wu SY, McInnes C, Zheleva D, Walkinshaw MD, Fischer PM. Wang S, et al. Among authors: fischer pm. J Med Chem. 2004 Mar 25;47(7):1662-75. doi: 10.1021/jm0309957. J Med Chem. 2004. PMID: 15027857

6

Structural determinants of CDK4 inhibition and design of selective ATP competitive inhibitors.

McInnes C, Wang S, Anderson S, O'Boyle J, Jackson W, Kontopidis G, Meades C, Mezna M, Thomas M, Wood G, Lane DP, Fischer PM. McInnes C, et al. Among authors: fischer pm. Chem Biol. 2004 Apr;11(4):525-34. doi: 10.1016/j.chembiol.2004.03.022. Chem Biol. 2004. PMID: 15123247

7

Synthesis and biological activity of 2-anilino-4-(1H-pyrrol-3-yl) pyrimidine CDK inhibitors.

Wang S, Wood G, Meades C, Griffiths G, Midgley C, McNae I, McInnes C, Anderson S, Jackson W, Mezna M, Yuill R, Walkinshaw M, Fischer PM. Wang S, et al. Among authors: fischer pm. Bioorg Med Chem Lett. 2004 Aug 16;14(16):4237-40. doi: 10.1016/j.bmcl.2004.06.012. Bioorg Med Chem Lett. 2004. PMID: 15261277

8

Differential binding of inhibitors to active and inactive CDK2 provides insights for drug design.

Kontopidis G, McInnes C, Pandalaneni SR, McNae I, Gibson D, Mezna M, Thomas M, Wood G, Wang S, Walkinshaw MD, Fischer PM. Kontopidis G, et al. Among authors: fischer pm. Chem Biol. 2006 Feb;13(2):201-11. doi: 10.1016/j.chembiol.2005.11.011. Chem Biol. 2006. PMID: 16492568

9

Synthesis and biological activity of conjugates between paclitaxel and the cell delivery vector penetratin.

Wang S, Zhelev NZ, Duff S, Fischer PM. Wang S, et al. Among authors: fischer pm. Bioorg Med Chem Lett. 2006 May 15;16(10):2628-31. doi: 10.1016/j.bmcl.2006.02.035. Epub 2006 Mar 2. Bioorg Med Chem Lett. 2006. PMID: 16513344

10

4-arylazo-3,5-diamino-1H-pyrazole CDK inhibitors: SAR study, crystal structure in complex with CDK2, selectivity, and cellular effects.

Krystof V, Cankar P, Frysová I, Slouka J, Kontopidis G, Dzubák P, Hajdúch M, Srovnal J, de Azevedo WF Jr, Orság M, Paprskárová M, Rolcík J, Látr A, Fischer PM, Strnad M. Krystof V, et al. Among authors: fischer pm. J Med Chem. 2006 Nov 2;49(22):6500-9. doi: 10.1021/jm0605740. J Med Chem. 2006. PMID: 17064068

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

198 results

Search Page

Filters