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Human rotavirus VP6-specific antibodies mediate intracellular neutralization by binding to a quaternary structure in the transcriptional pore.
Aiyegbo MS, Sapparapu G, Spiller BW, Eli IM, Williams DR, Kim R, Lee DE, Liu T, Li S, Woods VL Jr, Nannemann DP, Meiler J, Stewart PL, Crowe JE Jr. Aiyegbo MS, et al. Among authors: sapparapu g. PLoS One. 2013 May 9;8(5):e61101. doi: 10.1371/journal.pone.0061101. Print 2013. PLoS One. 2013. PMID: 23671563 Free PMC article.
Mechanism of human antibody-mediated neutralization of Marburg virus.
Flyak AI, Ilinykh PA, Murin CD, Garron T, Shen X, Fusco ML, Hashiguchi T, Bornholdt ZA, Slaughter JC, Sapparapu G, Klages C, Ksiazek TG, Ward AB, Saphire EO, Bukreyev A, Crowe JE Jr. Flyak AI, et al. Among authors: sapparapu g. Cell. 2015 Feb 26;160(5):893-903. doi: 10.1016/j.cell.2015.01.031. Cell. 2015. PMID: 25723164 Free PMC article.
Cryo-EM structures elucidate neutralizing mechanisms of anti-chikungunya human monoclonal antibodies with therapeutic activity.
Long F, Fong RH, Austin SK, Chen Z, Klose T, Fokine A, Liu Y, Porta J, Sapparapu G, Akahata W, Doranz BJ, Crowe JE Jr, Diamond MS, Rossmann MG. Long F, et al. Among authors: sapparapu g. Proc Natl Acad Sci U S A. 2015 Nov 10;112(45):13898-903. doi: 10.1073/pnas.1515558112. Epub 2015 Oct 26. Proc Natl Acad Sci U S A. 2015. PMID: 26504196 Free PMC article.
Dengue Virus prM-Specific Human Monoclonal Antibodies with Virus Replication-Enhancing Properties Recognize a Single Immunodominant Antigenic Site.
Smith SA, Nivarthi UK, de Alwis R, Kose N, Sapparapu G, Bombardi R, Kahle KM, Pfaff JM, Lieberman S, Doranz BJ, de Silva AM, Crowe JE Jr. Smith SA, et al. Among authors: sapparapu g. J Virol. 2015 Oct 28;90(2):780-9. doi: 10.1128/JVI.01805-15. Print 2016 Jan 15. J Virol. 2015. PMID: 26512092 Free PMC article.
Structural basis for norovirus neutralization by an HBGA blocking human IgA antibody.
Shanker S, Czakó R, Sapparapu G, Alvarado G, Viskovska M, Sankaran B, Atmar RL, Crowe JE Jr, Estes MK, Prasad BV. Shanker S, et al. Among authors: sapparapu g. Proc Natl Acad Sci U S A. 2016 Oct 4;113(40):E5830-E5837. doi: 10.1073/pnas.1609990113. Epub 2016 Sep 19. Proc Natl Acad Sci U S A. 2016. PMID: 27647885 Free PMC article.
Isolation and Characterization of Broad and Ultrapotent Human Monoclonal Antibodies with Therapeutic Activity against Chikungunya Virus.
Smith SA, Silva LA, Fox JM, Flyak AI, Kose N, Sapparapu G, Khomandiak S, Ashbrook AW, Kahle KM, Fong RH, Swayne S, Doranz BJ, McGee CE, Heise MT, Pal P, Brien JD, Austin SK, Diamond MS, Dermody TS, Crowe JE Jr. Smith SA, et al. Among authors: sapparapu g. Cell Host Microbe. 2015 Jul 8;18(1):86-95. doi: 10.1016/j.chom.2015.06.009. Cell Host Microbe. 2015. PMID: 26159721 Free PMC article.
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