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Page 1
Renal effects induced by prolonged mPGES1 inhibition.
Salazar F, Vazquez ML, Masferrer JL, Mbalaviele G, Llinas MT, Saez F, Arhancet G, Salazar FJ. Salazar F, et al. Among authors: vazquez ml. Am J Physiol Renal Physiol. 2014 Jan 1;306(1):F68-74. doi: 10.1152/ajprenal.00492.2013. Epub 2013 Nov 6. Am J Physiol Renal Physiol. 2014. PMID: 24197070 Free article.
Distinction of microsomal prostaglandin E synthase-1 (mPGES-1) inhibition from cyclooxygenase-2 inhibition in cells using a novel, selective mPGES-1 inhibitor.
Mbalaviele G, Pauley AM, Shaffer AF, Zweifel BS, Mathialagan S, Mnich SJ, Nemirovskiy OV, Carter J, Gierse JK, Wang JL, Vazquez ML, Moore WM, Masferrer JL. Mbalaviele G, et al. Among authors: vazquez ml. Biochem Pharmacol. 2010 May 15;79(10):1445-54. doi: 10.1016/j.bcp.2010.01.003. Epub 2010 Jan 11. Biochem Pharmacol. 2010. PMID: 20067770
Discovery and SAR of PF-4693627, a potent, selective and orally bioavailable mPGES-1 inhibitor for the potential treatment of inflammation.
Arhancet GB, Walker DP, Metz S, Fobian YM, Heasley SE, Carter JS, Springer JR, Jones DE, Hayes MJ, Shaffer AF, Jerome GM, Baratta MT, Zweifel B, Moore WM, Masferrer JL, Vazquez ML. Arhancet GB, et al. Among authors: vazquez ml. Bioorg Med Chem Lett. 2013 Feb 15;23(4):1114-9. doi: 10.1016/j.bmcl.2012.11.109. Epub 2012 Dec 6. Bioorg Med Chem Lett. 2013. PMID: 23260349
Novel benzoxazole inhibitors of mPGES-1.
Kablaoui N, Patel S, Shao J, Demian D, Hoffmaster K, Berlioz F, Vazquez ML, Moore WM, Nugent RA. Kablaoui N, et al. Among authors: vazquez ml. Bioorg Med Chem Lett. 2013 Feb 1;23(3):907-11. doi: 10.1016/j.bmcl.2012.10.040. Epub 2012 Oct 16. Bioorg Med Chem Lett. 2013. PMID: 23266122
Synthesis and biological evaluation of substituted benzoxazoles as inhibitors of mPGES-1: use of a conformation-based hypothesis to facilitate compound design.
Walker DP, Arhancet GB, Lu HF, Heasley SE, Metz S, Kablaoui NM, Franco FM, Hanau CE, Scholten JA, Springer JR, Fobian YM, Carter JS, Xing L, Yang S, Shaffer AF, Jerome GM, Baratta MT, Moore WM, Vazquez ML. Walker DP, et al. Among authors: vazquez ml. Bioorg Med Chem Lett. 2013 Feb 15;23(4):1120-6. doi: 10.1016/j.bmcl.2012.11.107. Epub 2012 Dec 12. Bioorg Med Chem Lett. 2013. PMID: 23298810
Homo-timeric structural model of human microsomal prostaglandin E synthase-1 and characterization of its substrate/inhibitor binding interactions.
Xing L, Kurumbail RG, Frazier RB, Davies MS, Fujiwara H, Weinberg RA, Gierse JK, Caspers N, Carter JS, McDonald JJ, Moore WM, Vazquez ML. Xing L, et al. Among authors: vazquez ml. J Comput Aided Mol Des. 2009 Jan;23(1):13-24. doi: 10.1007/s10822-008-9233-4. Epub 2008 Sep 6. J Comput Aided Mol Des. 2009. PMID: 18777160
Understanding the health system drivers of delayed cancer diagnosis in public healthcare networks of Chile, Colombia and Ecuador: A qualitative study with health professionals, managers and policymakers.
Vargas I, Mogollón-Pérez AS, Eguiguren P, Torres AL, Peralta A, Rubio-Valera M, Jervelund SS, Borras JM, Dias S, Vázquez ML; EquityCancer-LA project. Vargas I, et al. Among authors: vazquez ml. Soc Sci Med. 2024 Nov 15;365:117499. doi: 10.1016/j.socscimed.2024.117499. Online ahead of print. Soc Sci Med. 2024. PMID: 39626381 Free article.
111 results