Akagi K - Search Results

1

Genome-wide analysis of HPV integration in human cancers reveals recurrent, focal genomic instability.

Akagi K, Li J, Broutian TR, Padilla-Nash H, Xiao W, Jiang B, Rocco JW, Teknos TN, Kumar B, Wangsa D, He D, Ried T, Symer DE, Gillison ML. Akagi K, et al. Genome Res. 2014 Feb;24(2):185-99. doi: 10.1101/gr.164806.113. Epub 2013 Nov 7. Genome Res. 2014. PMID: 24201445 Free PMC article.

2

Human papillomavirus and the landscape of secondary genetic alterations in oral cancers.

Gillison ML, Akagi K, Xiao W, Jiang B, Pickard RKL, Li J, Swanson BJ, Agrawal AD, Zucker M, Stache-Crain B, Emde AK, Geiger HM, Robine N, Coombes KR, Symer DE. Gillison ML, et al. Among authors: akagi k. Genome Res. 2019 Jan;29(1):1-17. doi: 10.1101/gr.241141.118. Epub 2018 Dec 18. Genome Res. 2019. PMID: 30563911 Free PMC article. Clinical Trial.

3

Human papillomavirus insertions identify the PIM family of serine/threonine kinases as targetable driver genes in head and neck squamous cell carcinoma.

Broutian TR, Jiang B, Li J, Akagi K, Gui S, Zhou Z, Xiao W, Symer DE, Gillison ML. Broutian TR, et al. Among authors: akagi k. Cancer Lett. 2020 Apr 28;476:23-33. doi: 10.1016/j.canlet.2020.01.012. Epub 2020 Jan 17. Cancer Lett. 2020. PMID: 31958486 Free PMC article.

4

Diverse tumorigenic consequences of human papillomavirus integration in primary oropharyngeal cancers.

Symer DE, Akagi K, Geiger HM, Song Y, Li G, Emde AK, Xiao W, Jiang B, Corvelo A, Toussaint NC, Li J, Agrawal A, Ozer E, El-Naggar AK, Du Z, Shewale JB, Stache-Crain B, Zucker M, Robine N, Coombes KR, Gillison ML. Symer DE, et al. Among authors: akagi k. Genome Res. 2022 Jan;32(1):55-70. doi: 10.1101/gr.275911.121. Epub 2021 Dec 13. Genome Res. 2022. PMID: 34903527 Free PMC article.

5

Extensive variation between inbred mouse strains due to endogenous L1 retrotransposition.

Akagi K, Li J, Stephens RM, Volfovsky N, Symer DE. Akagi K, et al. Genome Res. 2008 Jun;18(6):869-80. doi: 10.1101/gr.075770.107. Epub 2008 Apr 1. Genome Res. 2008. PMID: 18381897 Free PMC article.

6

Mouse endogenous retroviruses can trigger premature transcriptional termination at a distance.

Li J, Akagi K, Hu Y, Trivett AL, Hlynialuk CJ, Swing DA, Volfovsky N, Morgan TC, Golubeva Y, Stephens RM, Smith DE, Symer DE. Li J, et al. Among authors: akagi k. Genome Res. 2012 May;22(5):870-84. doi: 10.1101/gr.130740.111. Epub 2012 Feb 23. Genome Res. 2012. PMID: 22367191 Free PMC article.

7

How do mammalian transposons induce genetic variation? A conceptual framework: the age, structure, allele frequency, and genome context of transposable elements may define their wide-ranging biological impacts.

Akagi K, Li J, Symer DE. Akagi K, et al. Bioessays. 2013 Apr;35(4):397-407. doi: 10.1002/bies.201200133. Epub 2013 Jan 14. Bioessays. 2013. PMID: 23319453 Free PMC article.

8

HPV integration hijacks and multimerizes a cellular enhancer to generate a viral-cellular super-enhancer that drives high viral oncogene expression.

Warburton A, Redmond CJ, Dooley KE, Fu H, Gillison ML, Akagi K, Symer DE, Aladjem MI, McBride AA. Warburton A, et al. Among authors: akagi k. PLoS Genet. 2018 Jan 24;14(1):e1007179. doi: 10.1371/journal.pgen.1007179. eCollection 2018 Jan. PLoS Genet. 2018. PMID: 29364907 Free PMC article.

9

An antisense promoter in mouse L1 retrotransposon open reading frame-1 initiates expression of diverse fusion transcripts and limits retrotransposition.

Li J, Kannan M, Trivett AL, Liao H, Wu X, Akagi K, Symer DE. Li J, et al. Among authors: akagi k. Nucleic Acids Res. 2014 Apr;42(7):4546-62. doi: 10.1093/nar/gku091. Epub 2014 Feb 3. Nucleic Acids Res. 2014. PMID: 24493738 Free PMC article.

10

Merkel Cell Polyomavirus Exhibits Dominant Control of the Tumor Genome and Transcriptome in Virus-Associated Merkel Cell Carcinoma.

Starrett GJ, Marcelus C, Cantalupo PG, Katz JP, Cheng J, Akagi K, Thakuria M, Rabinowits G, Wang LC, Symer DE, Pipas JM, Harris RS, DeCaprio JA. Starrett GJ, et al. Among authors: akagi k. mBio. 2017 Jan 3;8(1):e02079-16. doi: 10.1128/mBio.02079-16. mBio. 2017. PMID: 28049147 Free PMC article.

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