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Page 1
Genetics. Genetics driving epigenetics.
Furey TS, Sethupathy P. Furey TS, et al. Among authors: sethupathy p. Science. 2013 Nov 8;342(6159):705-6. doi: 10.1126/science.1246755. Science. 2013. PMID: 24202168 No abstract available.
Global epigenomic analysis of primary human pancreatic islets provides insights into type 2 diabetes susceptibility loci.
Stitzel ML, Sethupathy P, Pearson DS, Chines PS, Song L, Erdos MR, Welch R, Parker SC, Boyle AP, Scott LJ; NISC Comparative Sequencing Program; Margulies EH, Boehnke M, Furey TS, Crawford GE, Collins FS. Stitzel ML, et al. Among authors: sethupathy p. Cell Metab. 2010 Nov 3;12(5):443-55. doi: 10.1016/j.cmet.2010.09.012. Cell Metab. 2010. PMID: 21035756 Free PMC article.
MicroRNAs Classify Different Disease Behavior Phenotypes of Crohn's Disease and May Have Prognostic Utility.
Peck BC, Weiser M, Lee SE, Gipson GR, Iyer VB, Sartor RB, Herfarth HH, Long MD, Hansen JJ, Isaacs KL, Trembath DG, Rahbar R, Sadiq TS, Furey TS, Sethupathy P, Sheikh SZ. Peck BC, et al. Among authors: sethupathy p. Inflamm Bowel Dis. 2015 Sep;21(9):2178-87. doi: 10.1097/MIB.0000000000000478. Inflamm Bowel Dis. 2015. PMID: 26164662 Free PMC article.
Colonic epithelial miR-31 associates with the development of Crohn's phenotypes.
Keith BP, Barrow JB, Toyonaga T, Kazgan N, O'Connor MH, Shah ND, Schaner MS, Wolber EA, Trad OK, Gipson GR, Pitman WA, Kanke M, Saxena SJ, Chaumont N, Sadiq TS, Koruda MJ, Cotney PA, Allbritton N, Trembath DG, Sylvester F, Furey TS, Sethupathy P, Sheikh SZ. Keith BP, et al. Among authors: sethupathy p. JCI Insight. 2018 Oct 4;3(19):e122788. doi: 10.1172/jci.insight.122788. JCI Insight. 2018. PMID: 30282822 Free PMC article.
Redefining the IBDs using genome-scale molecular phenotyping.
Furey TS, Sethupathy P, Sheikh SZ. Furey TS, et al. Among authors: sethupathy p. Nat Rev Gastroenterol Hepatol. 2019 May;16(5):296-311. doi: 10.1038/s41575-019-0118-x. Nat Rev Gastroenterol Hepatol. 2019. PMID: 30787446 Free PMC article. Review.
Decreased Colonic Activin Receptor-Like Kinase 1 Disrupts Epithelial Barrier Integrity in Patients With Crohn's Disease.
Toyonaga T, Steinbach EC, Keith BP, Barrow JB, Schaner MR, Wolber EA, Beasley C, Huling J, Wang Y, Allbritton NL, Chaumont N, Sadiq TS, Koruda MJ, Jain A, Long MD, Barnes EL, Herfarth HH, Isaacs KL, Hansen JJ, Shanahan MT, Rahbar R, Furey TS, Sethupathy P, Sheikh SZ. Toyonaga T, et al. Among authors: sethupathy p. Cell Mol Gastroenterol Hepatol. 2020;10(4):779-796. doi: 10.1016/j.jcmgh.2020.06.005. Epub 2020 Jun 16. Cell Mol Gastroenterol Hepatol. 2020. PMID: 32561494 Free PMC article.
Increased Colonic Expression of ACE2 Associates with Poor Prognosis in Crohn's disease.
Toyonaga T, Araba KC, Kennedy MM, Keith BP, Wolber EA, Beasley C, Steinbach EC, Schaner MR, Jain A, Long MD, Barnes EL, Herfarth HH, Isaacs KL, Hansen JJ, Kapadia M, Gaston Guillem J, Koruda MJ, Rahbar R, Sadiq T, Gulati AS, Sethupathy P, Furey TS, Ehre C, Sheikh SZ. Toyonaga T, et al. Among authors: sethupathy p. bioRxiv [Preprint]. 2020 Nov 24:2020.11.24.396382. doi: 10.1101/2020.11.24.396382. bioRxiv. 2020. Update in: Sci Rep. 2021 Jun 29;11(1):13533. doi: 10.1038/s41598-021-92979-2 PMID: 33269348 Free PMC article. Updated. Preprint.
Increased colonic expression of ACE2 associates with poor prognosis in Crohn's disease.
Toyonaga T, Araba KC, Kennedy MM, Keith BP, Wolber EA, Beasley C, Steinbach EC, Schaner MR, Jain A, Long MD, Barnes EL, Herfarth HH, Isaacs KL, Hansen JJ, Kapadia MR, Guillem JG, Gulati AS, Sethupathy P, Furey TS, Ehre C, Sheikh SZ. Toyonaga T, et al. Among authors: sethupathy p. Sci Rep. 2021 Jun 29;11(1):13533. doi: 10.1038/s41598-021-92979-2. Sci Rep. 2021. PMID: 34188154 Free PMC article.
Single-Cell Analysis Reveals Unexpected Cellular Changes and Transposon Expression Signatures in the Colonic Epithelium of Treatment-Naïve Adult Crohn's Disease Patients.
Kanke M, Kennedy Ng MM, Connelly S, Singh M, Schaner M, Shanahan MT, Wolber EA, Beasley C, Lian G, Jain A, Long MD, Barnes EL, Herfarth HH, Isaacs KL, Hansen JJ, Kapadia M, Guillem JG, Feschotte C, Furey TS, Sheikh SZ, Sethupathy P. Kanke M, et al. Among authors: sethupathy p. Cell Mol Gastroenterol Hepatol. 2022;13(6):1717-1740. doi: 10.1016/j.jcmgh.2022.02.005. Epub 2022 Feb 12. Cell Mol Gastroenterol Hepatol. 2022. PMID: 35158099 Free PMC article.
Aberrant miR-29 is a predictive feature of severe phenotypes in pediatric Crohn's disease.
Shumway AJ, Shanahan MT, Hollville E, Chen K, Beasley C, Villanueva JW, Albert S, Lian G, Cure MR, Schaner M, Zhu LC, Bantumilli S, Deshmukh M, Furey TS, Sheikh SZ, Sethupathy P. Shumway AJ, et al. Among authors: sethupathy p. JCI Insight. 2024 Feb 22;9(4):e168800. doi: 10.1172/jci.insight.168800. JCI Insight. 2024. PMID: 38385744 Free PMC article.
149 results