Laufersweiler M - Search Results

1

Framework for identifying chemicals with structural features associated with the potential to act as developmental or reproductive toxicants.

Wu S, Fisher J, Naciff J, Laufersweiler M, Lester C, Daston G, Blackburn K. Wu S, et al. Among authors: laufersweiler m. Chem Res Toxicol. 2013 Dec 16;26(12):1840-61. doi: 10.1021/tx400226u. Epub 2013 Nov 22. Chem Res Toxicol. 2013. PMID: 24206190

2

Structure activity relationship (SAR) toxicological assessments: The role of expert judgment.

Lester C, Reis A, Laufersweiler M, Wu S, Blackburn K. Lester C, et al. Among authors: laufersweiler m. Regul Toxicol Pharmacol. 2018 Feb;92:390-406. doi: 10.1016/j.yrtph.2017.12.026. Epub 2018 Jan 4. Regul Toxicol Pharmacol. 2018. PMID: 29305951

3

Letter to the editor.

Lester CC, Wu S, Naciff J, Laufersweiler M, Daston G. Lester CC, et al. Among authors: laufersweiler m. Toxicol Sci. 2023 Jan 31;191(1):192. doi: 10.1093/toxsci/kfac111. Toxicol Sci. 2023. PMID: 36269224 No abstract available.

4

Correlation of chemical structure with reproductive and developmental toxicity as it relates to the use of the threshold of toxicological concern.

Laufersweiler MC, Gadagbui B, Baskerville-Abraham IM, Maier A, Willis A, Scialli AR, Carr GJ, Felter SP, Blackburn K, Daston G. Laufersweiler MC, et al. Regul Toxicol Pharmacol. 2012 Feb;62(1):160-82. doi: 10.1016/j.yrtph.2011.09.004. Epub 2011 Oct 10. Regul Toxicol Pharmacol. 2012. PMID: 22019814

5

Threshold of Toxicological Concern: Extending the chemical space by inclusion of a highly curated dataset for organosilicon compounds.

Schmitt BG, Jensen E, Laufersweiler MC, Rose JL. Schmitt BG, et al. Among authors: laufersweiler mc. Regul Toxicol Pharmacol. 2021 Dec;127:105074. doi: 10.1016/j.yrtph.2021.105074. Epub 2021 Oct 30. Regul Toxicol Pharmacol. 2021. PMID: 34757112 Free article.

6

Bolstering the existing database supporting the non-cancer Threshold of Toxicological Concern values with toxicity data on fragrance-related materials.

Patel A, Joshi K, Rose J, Laufersweiler M, Felter SP, Api AM. Patel A, et al. Among authors: laufersweiler m. Regul Toxicol Pharmacol. 2020 Oct;116:104718. doi: 10.1016/j.yrtph.2020.104718. Epub 2020 Jun 27. Regul Toxicol Pharmacol. 2020. PMID: 32603678 Free article.

7

Design and synthesis of novel N-sulfonyl-2-indole carboxamides as potent PPAR-gamma binding agents with potential application to the treatment of osteoporosis.

Hopkins CR, O'neil SV, Laufersweiler MC, Wang Y, Pokross M, Mekel M, Evdokimov A, Walter R, Kontoyianni M, Petrey ME, Sabatakos G, Roesgen JT, Richardson E, Demuth TP Jr. Hopkins CR, et al. Among authors: laufersweiler mc. Bioorg Med Chem Lett. 2006 Nov 1;16(21):5659-63. doi: 10.1016/j.bmcl.2006.08.003. Epub 2006 Aug 21. Bioorg Med Chem Lett. 2006. PMID: 16919947

8

Synthesis and evaluation of thiazepines as interleukin-1beta converting enzyme (ICE) inhibitors.

Ellis CD, Oppong KA, Laufersweiler MC, O'Neil SV, Soper DL, Wang Y, Wos JA, Fancher AN, Lu W, Suchanek MK, Wang RL, De B, Demuth TP Jr. Ellis CD, et al. Bioorg Med Chem Lett. 2006 Sep 15;16(18):4728-32. doi: 10.1016/j.bmcl.2006.07.016. Epub 2006 Jul 25. Bioorg Med Chem Lett. 2006. PMID: 16870441

9

Synthesis and evaluation of unsaturated caprolactams as interleukin-1beta converting enzyme (ICE) inhibitors.

Wang Y, O'Neil SV, Wos JA, Oppong KA, Laufersweiler MC, Soper DL, Ellis CD, Baize MW, Fancher AN, Lu W, Suchanek MK, Wang RL, Schwecke WP, Cruze CA, Buchalova M, Belkin M, De B, Demuth TP Jr. Wang Y, et al. Among authors: laufersweiler mc. Bioorg Med Chem. 2007 Feb 1;15(3):1311-22. doi: 10.1016/j.bmc.2006.11.011. Epub 2006 Nov 10. Bioorg Med Chem. 2007. PMID: 17127070

10

Discovery of novel conformationally restricted diazocan peptidomimetics as inhibitors of interleukin-1beta synthesis.

Oppong KA, Ellis CD, Laufersweiler MC, O'Neil SV, Wang Y, Soper DL, Baize MW, Wos JA, De B, Bosch GK, Fancher AN, Lu W, Suchanek MK, Wang RL, Demuth TP Jr. Oppong KA, et al. Bioorg Med Chem Lett. 2005 Oct 1;15(19):4291-4. doi: 10.1016/j.bmcl.2005.06.050. Bioorg Med Chem Lett. 2005. PMID: 16046125

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