Figler R - Search Results

1

The second extracellular loop of the adenosine A1 receptor mediates activity of allosteric enhancers.

Kennedy DP, McRobb FM, Leonhardt SA, Purdy M, Figler H, Marshall MA, Chordia M, Figler R, Linden J, Abagyan R, Yeager M. Kennedy DP, et al. Among authors: figler h, figler r. Mol Pharmacol. 2014 Feb;85(2):301-9. doi: 10.1124/mol.113.088682. Epub 2013 Nov 11. Mol Pharmacol. 2014. PMID: 24217444 Free PMC article.

2

Reconstitution of recombinant bovine A1 adenosine receptors in Sf9 cell membranes with recombinant G proteins of defined composition.

Figler RA, Graber SG, Lindorfer MA, Yasuda H, Linden J, Garrison JC. Figler RA, et al. Mol Pharmacol. 1996 Dec;50(6):1587-95. Mol Pharmacol. 1996. PMID: 8967981

3

The structure and function of A1 and A2B adenosine receptors.

Linden J, Auchampach JA, Jin X, Figler RA. Linden J, et al. Among authors: figler ra. Life Sci. 1998;62(17-18):1519-24. doi: 10.1016/s0024-3205(98)00100-3. Life Sci. 1998. PMID: 9585129

4

P-selectin-mediated platelet-neutrophil aggregate formation activates neutrophils in mouse and human sickle cell disease.

Polanowska-Grabowska R, Wallace K, Field JJ, Chen L, Marshall MA, Figler R, Gear AR, Linden J. Polanowska-Grabowska R, et al. Among authors: figler r. Arterioscler Thromb Vasc Biol. 2010 Dec;30(12):2392-9. doi: 10.1161/ATVBAHA.110.211615. Epub 2010 Nov 11. Arterioscler Thromb Vasc Biol. 2010. PMID: 21071696 Free PMC article.

5

The A2B adenosine receptor impairs the maturation and immunogenicity of dendritic cells.

Wilson JM, Ross WG, Agbai ON, Frazier R, Figler RA, Rieger J, Linden J, Ernst PB. Wilson JM, et al. Among authors: figler ra. J Immunol. 2009 Apr 15;182(8):4616-23. doi: 10.4049/jimmunol.0801279. J Immunol. 2009. PMID: 19342636 Free PMC article.

6

Reconstitution of bovine A1 adenosine receptors and G proteins in phospholipid vesicles: betagamma-subunit composition influences guanine nucleotide exchange and agonist binding.

Figler RA, Lindorfer MA, Graber SG, Garrison JC, Linden J. Figler RA, et al. Biochemistry. 1997 Dec 23;36(51):16288-99. doi: 10.1021/bi972000q. Biochemistry. 1997. PMID: 9405064

7

Links between insulin resistance, adenosine A2B receptors, and inflammatory markers in mice and humans.

Figler RA, Wang G, Srinivasan S, Jung DY, Zhang Z, Pankow JS, Ravid K, Fredholm B, Hedrick CC, Rich SS, Kim JK, LaNoue KF, Linden J. Figler RA, et al. Diabetes. 2011 Feb;60(2):669-79. doi: 10.2337/db10-1070. Diabetes. 2011. PMID: 21270276 Free PMC article.

8

Contribution of adenosine A(2B) receptors in Clostridium difficile intoxication and infection.

Warren CA, Li Y, Calabrese GM, Freire RS, Zaja-Milatovic S, van Opstal E, Figler RA, Linden J, Guerrant RL. Warren CA, et al. Infect Immun. 2012 Dec;80(12):4463-73. doi: 10.1128/IAI.00782-12. Epub 2012 Oct 8. Infect Immun. 2012. PMID: 23045479 Free PMC article.

9

Effects of adenosine A₂A receptor activation and alanyl-glutamine in Clostridium difficile toxin-induced ileitis in rabbits and cecitis in mice.

Warren CA, Calabrese GM, Li Y, Pawlowski SW, Figler RA, Rieger J, Ernst PB, Linden J, Guerrant RL. Warren CA, et al. BMC Infect Dis. 2012 Jan 20;12:13. doi: 10.1186/1471-2334-12-13. BMC Infect Dis. 2012. PMID: 22264229 Free PMC article.

10

A2A adenosine receptor (AR) activation inhibits pro-inflammatory cytokine production by human CD4+ helper T cells and regulates Helicobacter-induced gastritis and bacterial persistence.

Alam MS, Kurtz CC, Wilson JM, Burnette BR, Wiznerowicz EB, Ross WG, Rieger JM, Figler RA, Linden J, Crowe SE, Ernst PB. Alam MS, et al. Among authors: figler ra. Mucosal Immunol. 2009 May;2(3):232-42. doi: 10.1038/mi.2009.4. Epub 2009 Mar 4. Mucosal Immunol. 2009. PMID: 19262506 Free PMC article.

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