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Protein kinase C η is required for T cell activation and homeostatic proliferation.
Fu G, Hu J, Niederberger-Magnenat N, Rybakin V, Casas J, Yachi PP, Feldstein S, Ma B, Hoerter JA, Ampudia J, Rigaud S, Lambolez F, Gavin AL, Sauer K, Cheroutre H, Gascoigne NR. Fu G, et al. Among authors: hoerter ja. Sci Signal. 2011 Dec 6;4(202):ra84. doi: 10.1126/scisignal.2002058. Sci Signal. 2011. PMID: 22155788 Free PMC article.
GRB2-mediated recruitment of THEMIS to LAT is essential for thymocyte development.
Paster W, Brockmeyer C, Fu G, Simister PC, de Wet B, Martinez-Riaño A, Hoerter JA, Feller SM, Wülfing C, Gascoigne NR, Acuto O. Paster W, et al. Among authors: hoerter ja. J Immunol. 2013 Apr 1;190(7):3749-56. doi: 10.4049/jimmunol.1203389. Epub 2013 Mar 4. J Immunol. 2013. PMID: 23460737 Free PMC article.
Ligand-engaged TCR is triggered by Lck not associated with CD8 coreceptor.
Casas J, Brzostek J, Zarnitsyna VI, Hong JS, Wei Q, Hoerter JA, Fu G, Ampudia J, Zamoyska R, Zhu C, Gascoigne NR. Casas J, et al. Among authors: hoerter ja. Nat Commun. 2014 Nov 27;5:5624. doi: 10.1038/ncomms6624. Nat Commun. 2014. PMID: 25427562 Free PMC article.
Co-receptors and recognition of self at the immunological synapse.
Gascoigne NR, Zal T, Yachi PP, Hoerter JA. Gascoigne NR, et al. Among authors: hoerter ja. Curr Top Microbiol Immunol. 2010;340:171-89. doi: 10.1007/978-3-642-03858-7_9. Curr Top Microbiol Immunol. 2010. PMID: 19960314 Free PMC article. Review.
Inhibition of the Inositol Kinase Itpkb Augments Calcium Signaling in Lymphocytes and Reveals a Novel Strategy to Treat Autoimmune Disease.
Miller AT, Dahlberg C, Sandberg ML, Wen BG, Beisner DR, Hoerter JA, Parker A, Schmedt C, Stinson M, Avis J, Cienfuegos C, McPate M, Tranter P, Gosling M, Groot-Kormelink PJ, Dawson J, Pan S, Tian SS, Seidel HM, Cooke MP. Miller AT, et al. Among authors: hoerter ja. PLoS One. 2015 Jun 29;10(6):e0131071. doi: 10.1371/journal.pone.0131071. eCollection 2015. PLoS One. 2015. PMID: 26121493 Free PMC article.
38 results