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Activated ClpP kills persisters and eradicates a chronic biofilm infection.
Conlon BP, Nakayasu ES, Fleck LE, LaFleur MD, Isabella VM, Coleman K, Leonard SN, Smith RD, Adkins JN, Lewis K. Conlon BP, et al. Among authors: lafleur md. Nature. 2013 Nov 21;503(7476):365-70. doi: 10.1038/nature12790. Epub 2013 Nov 13. Nature. 2013. PMID: 24226776 Free PMC article.
Ureadepsipeptides as ClpP Activators.
Griffith EC, Zhao Y, Singh AP, Conlon BP, Tangallapally R, Shadrick WR, Liu J, Wallace MJ, Yang L, Elmore JM, Li Y, Zheng Z, Miller DJ, Cheramie MN, Lee RB, LaFleur MD, Lewis K, Lee RE. Griffith EC, et al. Among authors: lafleur md. ACS Infect Dis. 2019 Nov 8;5(11):1915-1925. doi: 10.1021/acsinfecdis.9b00245. Epub 2019 Oct 24. ACS Infect Dis. 2019. PMID: 31588734 Free PMC article.
Potentiation of azole antifungals by 2-adamantanamine.
Lafleur MD, Sun L, Lister I, Keating J, Nantel A, Long L, Ghannoum M, North J, Lee RE, Coleman K, Dahl T, Lewis K. Lafleur MD, et al. Antimicrob Agents Chemother. 2013 Aug;57(8):3585-92. doi: 10.1128/AAC.00294-13. Epub 2013 May 20. Antimicrob Agents Chemother. 2013. PMID: 23689724 Free PMC article.
The Discovery and Development of Thienopyrimidines as Inhibitors of Helicobacter pylori That Act through Inhibition of the Respiratory Complex I.
Mugengana AK, Vita NA, Brown Gandt A, Moran K, Agyapong G, Sharma LK, Griffith EC, Liu J, Yang L, Gavrish E, Hevener KE, LaFleur MD, Lee RE. Mugengana AK, et al. Among authors: lafleur md. ACS Infect Dis. 2021 May 14;7(5):1044-1058. doi: 10.1021/acsinfecdis.0c00300. Epub 2021 Jan 20. ACS Infect Dis. 2021. PMID: 33471519 Free PMC article.
13 results