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Trypanosoma brucei aquaglyceroporin 2 is a high-affinity transporter for pentamidine and melaminophenyl arsenic drugs and the main genetic determinant of resistance to these drugs.
Munday JC, Eze AA, Baker N, Glover L, Clucas C, Aguinaga Andrés D, Natto MJ, Teka IA, McDonald J, Lee RS, Graf FE, Ludin P, Burchmore RJ, Turner CM, Tait A, MacLeod A, Mäser P, Barrett MP, Horn D, De Koning HP. Munday JC, et al. Among authors: glover l. J Antimicrob Chemother. 2014 Mar;69(3):651-63. doi: 10.1093/jac/dkt442. Epub 2013 Nov 13. J Antimicrob Chemother. 2014. PMID: 24235095 Free PMC article.
Multiplex analysis of RNA interference defects in Trypanosoma brucei.
Alsford S, Glover L, Horn D. Alsford S, et al. Among authors: glover l. Mol Biochem Parasitol. 2005 Jan;139(1):129-32. doi: 10.1016/j.molbiopara.2004.11.001. Mol Biochem Parasitol. 2005. PMID: 15610827 Free PMC article. No abstract available.
High-throughput decoding of antitrypanosomal drug efficacy and resistance.
Alsford S, Eckert S, Baker N, Glover L, Sanchez-Flores A, Leung KF, Turner DJ, Field MC, Berriman M, Horn D. Alsford S, et al. Among authors: glover l. Nature. 2012 Jan 25;482(7384):232-6. doi: 10.1038/nature10771. Nature. 2012. PMID: 22278056 Free PMC article.
Trypanosomal histone γH2A and the DNA damage response.
Glover L, Horn D. Glover L, et al. Mol Biochem Parasitol. 2012 May;183(1):78-83. doi: 10.1016/j.molbiopara.2012.01.008. Epub 2012 Feb 14. Mol Biochem Parasitol. 2012. PMID: 22353557 Free PMC article.
Insights into antitrypanosomal drug mode-of-action from cytology-based profiling.
Thomas JA, Baker N, Hutchinson S, Dominicus C, Trenaman A, Glover L, Alsford S, Horn D. Thomas JA, et al. Among authors: glover l. PLoS Negl Trop Dis. 2018 Nov 26;12(11):e0006980. doi: 10.1371/journal.pntd.0006980. eCollection 2018 Nov. PLoS Negl Trop Dis. 2018. PMID: 30475806 Free PMC article.
342 results