Sun H - Search Results

1

Pyrido[2,3-d]pyrimidines: discovery and preliminary SAR of a novel series of DYRK1B and DYRK1A inhibitors.

Anderson K, Chen Y, Chen Z, Dominique R, Glenn K, He Y, Janson C, Luk KC, Lukacs C, Polonskaia A, Qiao Q, Railkar A, Rossman P, Sun H, Xiang Q, Vilenchik M, Wovkulich P, Zhang X. Anderson K, et al. Among authors: sun h. Bioorg Med Chem Lett. 2013 Dec 15;23(24):6610-5. doi: 10.1016/j.bmcl.2013.10.055. Epub 2013 Nov 1. Bioorg Med Chem Lett. 2013. PMID: 24239188

2

A predictive pharmacophore model of human melanocortin-4 receptor as derived from the solution structures of cyclic peptides.

Sun H, Greeley DN, Chu XJ, Cheung A, Danho W, Swistok J, Wang Y, Zhao C, Chen L, Fry DC. Sun H, et al. Bioorg Med Chem. 2004 May 15;12(10):2671-7. doi: 10.1016/j.bmc.2004.03.017. Bioorg Med Chem. 2004. PMID: 15110848

3

A naive bayes classifier for prediction of multidrug resistance reversal activity on the basis of atom typing.

Sun H. Sun H. J Med Chem. 2005 Jun 16;48(12):4031-9. doi: 10.1021/jm050180t. J Med Chem. 2005. PMID: 15943476

4

Support vector machines classification of hERG liabilities based on atom types.

Jia L, Sun H. Jia L, et al. Among authors: sun h. Bioorg Med Chem. 2008 Jun 1;16(11):6252-60. doi: 10.1016/j.bmc.2008.04.028. Epub 2008 Apr 16. Bioorg Med Chem. 2008. PMID: 18448342

5

Identification of potent Yes1 kinase inhibitors using a library screening approach.

Patel PR, Sun H, Li SQ, Shen M, Khan J, Thomas CJ, Davis MI. Patel PR, et al. Among authors: sun h. Bioorg Med Chem Lett. 2013 Aug 1;23(15):4398-403. doi: 10.1016/j.bmcl.2013.05.072. Epub 2013 May 29. Bioorg Med Chem Lett. 2013. PMID: 23787099 Free PMC article.

6

Selective small-molecule inhibitor reveals critical mitotic functions of human CDK1.

Vassilev LT, Tovar C, Chen S, Knezevic D, Zhao X, Sun H, Heimbrook DC, Chen L. Vassilev LT, et al. Among authors: sun h. Proc Natl Acad Sci U S A. 2006 Jul 11;103(28):10660-5. doi: 10.1073/pnas.0600447103. Epub 2006 Jul 3. Proc Natl Acad Sci U S A. 2006. PMID: 16818887 Free PMC article.

7

Utilizing peptide structures as keys for unlocking challenging targets.

Fry D, Sun H. Fry D, et al. Among authors: sun h. Mini Rev Med Chem. 2006 Sep;6(9):979-87. doi: 10.2174/138955706778195171. Mini Rev Med Chem. 2006. PMID: 17017997 Review.

8

Molecular modeling of melanocortin receptors.

Sun H, Fry D. Sun H, et al. Curr Top Med Chem. 2007;7(11):1042-51. doi: 10.2174/156802607780906573. Curr Top Med Chem. 2007. PMID: 17584125 Review.

9

Discovery of NCT-501, a Potent and Selective Theophylline-Based Inhibitor of Aldehyde Dehydrogenase 1A1 (ALDH1A1).

Yang SM, Yasgar A, Miller B, Lal-Nag M, Brimacombe K, Hu X, Sun H, Wang A, Xu X, Nguyen K, Oppermann U, Ferrer M, Vasiliou V, Simeonov A, Jadhav A, Maloney DJ. Yang SM, et al. Among authors: sun h. J Med Chem. 2015 Aug 13;58(15):5967-78. doi: 10.1021/acs.jmedchem.5b00577. Epub 2015 Jul 24. J Med Chem. 2015. PMID: 26207746 Free PMC article.

10

Are hERG channel blockers also phospholipidosis inducers?

Sun H, Xia M, Shahane SA, Jadhav A, Austin CP, Huang R. Sun H, et al. Bioorg Med Chem Lett. 2013 Aug 15;23(16):4587-90. doi: 10.1016/j.bmcl.2013.06.034. Epub 2013 Jun 20. Bioorg Med Chem Lett. 2013. PMID: 23856051 Free PMC article.

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