Xiang L - Search Results

1

Ganetespib blocks HIF-1 activity and inhibits tumor growth, vascularization, stem cell maintenance, invasion, and metastasis in orthotopic mouse models of triple-negative breast cancer.

Xiang L, Gilkes DM, Chaturvedi P, Luo W, Hu H, Takano N, Liang H, Semenza GL. Xiang L, et al. J Mol Med (Berl). 2014 Feb;92(2):151-64. doi: 10.1007/s00109-013-1102-5. Epub 2013 Nov 20. J Mol Med (Berl). 2014. PMID: 24248265 Free PMC article.

2

Hypoxia-inducible factors mediate coordinated RhoA-ROCK1 expression and signaling in breast cancer cells.

Gilkes DM, Xiang L, Lee SJ, Chaturvedi P, Hubbi ME, Wirtz D, Semenza GL. Gilkes DM, et al. Among authors: xiang l. Proc Natl Acad Sci U S A. 2014 Jan 21;111(3):E384-93. doi: 10.1073/pnas.1321510111. Epub 2013 Dec 9. Proc Natl Acad Sci U S A. 2014. Retraction in: Proc Natl Acad Sci U S A. 2022 Sep 20;119(38):e2213288119. doi: 10.1073/pnas.2213288119. PMID: 24324133 Free PMC article. Retracted.

3

Hypoxia-inducible factors and RAB22A mediate formation of microvesicles that stimulate breast cancer invasion and metastasis.

Wang T, Gilkes DM, Takano N, Xiang L, Luo W, Bishop CJ, Chaturvedi P, Green JJ, Semenza GL. Wang T, et al. Among authors: xiang l. Proc Natl Acad Sci U S A. 2014 Aug 5;111(31):E3234-42. doi: 10.1073/pnas.1410041111. Epub 2014 Jun 17. Proc Natl Acad Sci U S A. 2014. PMID: 24938788 Free PMC article.

4

Hypoxia-inducible factors enhance glutamate signaling in cancer cells.

Hu H, Takano N, Xiang L, Gilkes DM, Luo W, Semenza GL. Hu H, et al. Among authors: xiang l. Oncotarget. 2014 Oct 15;5(19):8853-68. doi: 10.18632/oncotarget.2593. Oncotarget. 2014. PMID: 25326682 Free PMC article.

5

Hypoxia-inducible factors are required for chemotherapy resistance of breast cancer stem cells.

Samanta D, Gilkes DM, Chaturvedi P, Xiang L, Semenza GL. Samanta D, et al. Among authors: xiang l. Proc Natl Acad Sci U S A. 2014 Dec 16;111(50):E5429-38. doi: 10.1073/pnas.1421438111. Epub 2014 Dec 1. Proc Natl Acad Sci U S A. 2014. Retraction in: Proc Natl Acad Sci U S A. 2022 Sep 20;119(38):e2213289119. doi: 10.1073/pnas.2213289119. PMID: 25453096 Free PMC article. Retracted.

6

Hypoxia-inducible factor 1 mediates TAZ expression and nuclear localization to induce the breast cancer stem cell phenotype.

Xiang L, Gilkes DM, Hu H, Takano N, Luo W, Lu H, Bullen JW, Samanta D, Liang H, Semenza GL. Xiang L, et al. Oncotarget. 2014 Dec 30;5(24):12509-27. doi: 10.18632/oncotarget.2997. Oncotarget. 2014. PMID: 25587023 Free PMC article.

7

HIF-1α and TAZ serve as reciprocal co-activators in human breast cancer cells.

Xiang L, Gilkes DM, Hu H, Luo W, Bullen JW, Liang H, Semenza GL. Xiang L, et al. Oncotarget. 2015 May 20;6(14):11768-78. doi: 10.18632/oncotarget.4190. Oncotarget. 2015. PMID: 26059435 Free PMC article.

8

Chemotherapy triggers HIF-1-dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype.

Lu H, Samanta D, Xiang L, Zhang H, Hu H, Chen I, Bullen JW, Semenza GL. Lu H, et al. Among authors: xiang l. Proc Natl Acad Sci U S A. 2015 Aug 18;112(33):E4600-9. doi: 10.1073/pnas.1513433112. Epub 2015 Jul 30. Proc Natl Acad Sci U S A. 2015. PMID: 26229077 Free PMC article.

9

HIF-1 regulates CD47 expression in breast cancer cells to promote evasion of phagocytosis and maintenance of cancer stem cells.

Zhang H, Lu H, Xiang L, Bullen JW, Zhang C, Samanta D, Gilkes DM, He J, Semenza GL. Zhang H, et al. Among authors: xiang l. Proc Natl Acad Sci U S A. 2015 Nov 10;112(45):E6215-23. doi: 10.1073/pnas.1520032112. Epub 2015 Oct 28. Proc Natl Acad Sci U S A. 2015. PMID: 26512116 Free PMC article.

10

Hypoxia Selectively Enhances Integrin α₅β₁ Receptor Expression in Breast Cancer to Promote Metastasis.

Ju JA, Godet I, Ye IC, Byun J, Jayatilaka H, Lee SJ, Xiang L, Samanta D, Lee MH, Wu PH, Wirtz D, Semenza GL, Gilkes DM. Ju JA, et al. Among authors: xiang l. Mol Cancer Res. 2017 Jun;15(6):723-734. doi: 10.1158/1541-7786.MCR-16-0338. Epub 2017 Feb 17. Mol Cancer Res. 2017. PMID: 28213554 Free PMC article.

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