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The potent and broadly neutralizing human dengue virus-specific monoclonal antibody 1C19 reveals a unique cross-reactive epitope on the bc loop of domain II of the envelope protein.
Smith SA, de Alwis AR, Kose N, Harris E, Ibarra KD, Kahle KM, Pfaff JM, Xiang X, Doranz BJ, de Silva AM, Austin SK, Sukupolvi-Petty S, Diamond MS, Crowe JE Jr. Smith SA, et al. Among authors: pfaff jm. mBio. 2013 Nov 19;4(6):e00873-13. doi: 10.1128/mBio.00873-13. mBio. 2013. PMID: 24255124 Free PMC article.
Mapping the Human Memory B Cell and Serum Neutralizing Antibody Responses to Dengue Virus Serotype 4 Infection and Vaccination.
Nivarthi UK, Kose N, Sapparapu G, Widman D, Gallichotte E, Pfaff JM, Doranz BJ, Weiskopf D, Sette A, Durbin AP, Whitehead SS, Baric R, Crowe JE Jr, de Silva AM. Nivarthi UK, et al. Among authors: pfaff jm. J Virol. 2017 Feb 14;91(5):e02041-16. doi: 10.1128/JVI.02041-16. Print 2017 Mar 1. J Virol. 2017. PMID: 28031369 Free PMC article.
Broadly neutralizing antibodies with few somatic mutations and hepatitis C virus clearance.
Bailey JR, Flyak AI, Cohen VJ, Li H, Wasilewski LN, Snider AE, Wang S, Learn GH, Kose N, Loerinc L, Lampley R, Cox AL, Pfaff JM, Doranz BJ, Shaw GM, Ray SC, Crowe JE Jr. Bailey JR, et al. Among authors: pfaff jm. JCI Insight. 2017 May 4;2(9):e92872. doi: 10.1172/jci.insight.92872. eCollection 2017 May 4. JCI Insight. 2017. PMID: 28469084 Free PMC article.
Dengue virus envelope protein domain I/II hinge determines long-lived serotype-specific dengue immunity.
Messer WB, de Alwis R, Yount BL, Royal SR, Huynh JP, Smith SA, Crowe JE Jr, Doranz BJ, Kahle KM, Pfaff JM, White LJ, Sariol CA, de Silva AM, Baric RS. Messer WB, et al. Among authors: pfaff jm. Proc Natl Acad Sci U S A. 2014 Feb 4;111(5):1939-44. doi: 10.1073/pnas.1317350111. Epub 2014 Jan 2. Proc Natl Acad Sci U S A. 2014. Retraction in: Proc Natl Acad Sci U S A. 2015 May 19;112(20):E2738. doi: 10.1073/pnas.1506982112. PMID: 24385585 Free PMC article. Retracted.
Atomic-level functional model of dengue virus Envelope protein infectivity.
Christian EA, Kahle KM, Mattia K, Puffer BA, Pfaff JM, Miller A, Paes C, Davidson E, Doranz BJ. Christian EA, et al. Among authors: pfaff jm. Proc Natl Acad Sci U S A. 2013 Nov 12;110(46):18662-7. doi: 10.1073/pnas.1310962110. Epub 2013 Oct 24. Proc Natl Acad Sci U S A. 2013. PMID: 24158478 Free PMC article.
HCV E2 core structures and mAbs: something is still missing.
Castelli M, Clementi N, Sautto GA, Pfaff J, Kahle KM, Barnes T, Doranz BJ, Dal Peraro M, Clementi M, Burioni R, Mancini N. Castelli M, et al. Drug Discov Today. 2014 Dec;19(12):1964-70. doi: 10.1016/j.drudis.2014.08.011. Epub 2014 Aug 27. Drug Discov Today. 2014. PMID: 25172800 Free PMC article. Review.
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