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Haploinsufficiency of Apc leads to ineffective hematopoiesis.
Wang J, Fernald AA, Anastasi J, Le Beau MM, Qian Z. Wang J, et al. Among authors: fernald aa. Blood. 2010 Apr 29;115(17):3481-8. doi: 10.1182/blood-2009-11-251835. Epub 2010 Jan 11. Blood. 2010. PMID: 20065296 Free PMC article.
Retroviral insertional mutagenesis identifies the del(5q) genes, CXXC5, TIFAB and ETF1, as well as the Wnt pathway, as potential targets in del(5q) myeloid neoplasms.
Stoddart A, Qian Z, Fernald AA, Bergerson RJ, Wang J, Karrison T, Anastasi J, Bartom ET, Sarver AL, McNerney ME, Largaespada DA, Le Beau MM. Stoddart A, et al. Among authors: fernald aa. Haematologica. 2016 Jun;101(6):e232-6. doi: 10.3324/haematol.2015.139527. Epub 2016 Mar 4. Haematologica. 2016. PMID: 26944478 Free PMC article. No abstract available.
41 results