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Synthesis of piperlogs and analysis of their effects on cells.
Boskovic ZV, Hussain MM, Adams DJ, Dai M, Schreiber SL. Boskovic ZV, et al. Among authors: adams dj. Tetrahedron. 2013 Sep 9;69(36):10.1016/j.tet.2013.05.080. doi: 10.1016/j.tet.2013.05.080. Tetrahedron. 2013. PMID: 24273350 Free PMC article.
Integrative radiogenomic profiling of squamous cell lung cancer.
Abazeed ME, Adams DJ, Hurov KE, Tamayo P, Creighton CJ, Sonkin D, Giacomelli AO, Du C, Fries DF, Wong KK, Mesirov JP, Loeffler JS, Schreiber SL, Hammerman PS, Meyerson M. Abazeed ME, et al. Among authors: adams dj. Cancer Res. 2013 Oct 15;73(20):6289-98. doi: 10.1158/0008-5472.CAN-13-1616. Epub 2013 Aug 26. Cancer Res. 2013. PMID: 23980093 Free PMC article.
NAMPT is the cellular target of STF-31-like small-molecule probes.
Adams DJ, Ito D, Rees MG, Seashore-Ludlow B, Puyang X, Ramos AH, Cheah JH, Clemons PA, Warmuth M, Zhu P, Shamji AF, Schreiber SL. Adams DJ, et al. ACS Chem Biol. 2014 Oct 17;9(10):2247-54. doi: 10.1021/cb500347p. Epub 2014 Aug 7. ACS Chem Biol. 2014. PMID: 25058389 Free PMC article.
A genetic basis for the variation in the vulnerability of cancer to DNA damage.
Yard BD, Adams DJ, Chie EK, Tamayo P, Battaglia JS, Gopal P, Rogacki K, Pearson BE, Phillips J, Raymond DP, Pennell NA, Almeida F, Cheah JH, Clemons PA, Shamji A, Peacock CD, Schreiber SL, Hammerman PS, Abazeed ME. Yard BD, et al. Among authors: adams dj. Nat Commun. 2016 Apr 25;7:11428. doi: 10.1038/ncomms11428. Nat Commun. 2016. PMID: 27109210 Free PMC article.
Correlating chemical sensitivity and basal gene expression reveals mechanism of action.
Rees MG, Seashore-Ludlow B, Cheah JH, Adams DJ, Price EV, Gill S, Javaid S, Coletti ME, Jones VL, Bodycombe NE, Soule CK, Alexander B, Li A, Montgomery P, Kotz JD, Hon CS, Munoz B, Liefeld T, Dančík V, Haber DA, Clish CB, Bittker JA, Palmer M, Wagner BK, Clemons PA, Shamji AF, Schreiber SL. Rees MG, et al. Among authors: adams dj. Nat Chem Biol. 2016 Feb;12(2):109-16. doi: 10.1038/nchembio.1986. Epub 2015 Dec 14. Nat Chem Biol. 2016. PMID: 26656090 Free PMC article.
Melanoma Therapeutic Strategies that Select against Resistance by Exploiting MYC-Driven Evolutionary Convergence.
Singleton KR, Crawford L, Tsui E, Manchester HE, Maertens O, Liu X, Liberti MV, Magpusao AN, Stein EM, Tingley JP, Frederick DT, Boland GM, Flaherty KT, McCall SJ, Krepler C, Sproesser K, Herlyn M, Adams DJ, Locasale JW, Cichowski K, Mukherjee S, Wood KC. Singleton KR, et al. Among authors: adams dj. Cell Rep. 2017 Dec 5;21(10):2796-2812. doi: 10.1016/j.celrep.2017.11.022. Cell Rep. 2017. PMID: 29212027 Free PMC article.
Exploration of the mutational landscape of cutaneous leiomyoma confirms FH as a driver gene and identifies targeting purine metabolism as a potential therapeutic strategy.
van der Weyden L, Del Castillo Velasco-Herrera M, Cheema S, Wong K, Boccacino JM, Vermes I, Offord V, Droop A, Jones DRA, Anderson E, Hardy C, de Saint Aubain N, Ferguson PM, Mogler C, Rajan N, Frew D, Harms PW, Billings SD, Schatton D, Segarra-Mondejar M, Arends MJ, Ferreira I, Brenn T, Frezza C, Adams DJ. van der Weyden L, et al. Among authors: adams dj. Br J Dermatol. 2024 Nov 7:ljae432. doi: 10.1093/bjd/ljae432. Online ahead of print. Br J Dermatol. 2024. PMID: 39506538 No abstract available.
1,170 results