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Animal toxins influence voltage-gated sodium channel function.
Gilchrist J, Olivera BM, Bosmans F. Gilchrist J, et al. Among authors: bosmans f. Handb Exp Pharmacol. 2014;221:203-29. doi: 10.1007/978-3-642-41588-3_10. Handb Exp Pharmacol. 2014. PMID: 24737238 Free PMC article. Review.
Animal toxins can alter the function of Nav1.8 and Nav1.9.
Gilchrist J, Bosmans F. Gilchrist J, et al. Among authors: bosmans f. Toxins (Basel). 2012 Aug;4(8):620-32. doi: 10.3390/toxins4080620. Epub 2012 Aug 14. Toxins (Basel). 2012. PMID: 23012651 Free PMC article. Review.
Selective spider toxins reveal a role for the Nav1.1 channel in mechanical pain.
Osteen JD, Herzig V, Gilchrist J, Emrick JJ, Zhang C, Wang X, Castro J, Garcia-Caraballo S, Grundy L, Rychkov GY, Weyer AD, Dekan Z, Undheim EA, Alewood P, Stucky CL, Brierley SM, Basbaum AI, Bosmans F, King GF, Julius D. Osteen JD, et al. Among authors: bosmans f. Nature. 2016 Jun 23;534(7608):494-9. doi: 10.1038/nature17976. Epub 2016 Jun 6. Nature. 2016. PMID: 27281198 Free PMC article.
The tarantula toxin β/δ-TRTX-Pre1a highlights the importance of the S1-S2 voltage-sensor region for sodium channel subtype selectivity.
Wingerd JS, Mozar CA, Ussing CA, Murali SS, Chin YK, Cristofori-Armstrong B, Durek T, Gilchrist J, Vaughan CW, Bosmans F, Adams DJ, Lewis RJ, Alewood PF, Mobli M, Christie MJ, Rash LD. Wingerd JS, et al. Among authors: bosmans f. Sci Rep. 2017 Apr 20;7(1):974. doi: 10.1038/s41598-017-01129-0. Sci Rep. 2017. PMID: 28428547 Free PMC article.
90 results