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Rabies Virus Neutralizing Activity, Safety, and Immunogenicity of Recombinant Human Rabies Antibody Compared with Human Rabies Immunoglobulin in Healthy Adults.
Zhang JN, Meng YJ, Bai YH, Li YF, Yang LQ, Shi NM, Han HX, Gao J, Zhu LJ, Li SP, Zhang J, Zhao QH, Wang XQ, Wei JS, Ren LM, Cao CH, Chen C, Zhao W, Li L. Zhang JN, et al. Biomed Environ Sci. 2022 Sep 20;35(9):782-791. doi: 10.3967/bes2022.103. Biomed Environ Sci. 2022. PMID: 36189993 Free article. Clinical Trial.
Small molecule inhibits KCNQ channels with a non-blocking mechanism.
Li J, Yang Z, Zhang S, Ye Y, He J, Zhang Y, Han H, Kong W, Liu J, Min Y, Shen J, Mei L, Chen Z, Hou P, Guo J, Zhang Q, Yang H. Li J, et al. Among authors: han h. Nat Chem Biol. 2025 Jan 15. doi: 10.1038/s41589-024-01834-8. Online ahead of print. Nat Chem Biol. 2025. PMID: 39814994
De novo designed proteins neutralize lethal snake venom toxins.
Vázquez Torres S, Benard Valle M, Mackessy SP, Menzies SK, Casewell NR, Ahmadi S, Burlet NJ, Muratspahić E, Sappington I, Overath MD, Rivera-de-Torre E, Ledergerber J, Laustsen AH, Boddum K, Bera AK, Kang A, Brackenbrough E, Cardoso IA, Crittenden EP, Edge RJ, Decarreau J, Ragotte RJ, Pillai AS, Abedi M, Han HL, Gerben SR, Murray A, Skotheim R, Stuart L, Stewart L, Fryer TJA, Jenkins TP, Baker D. Vázquez Torres S, et al. Among authors: han hl. Nature. 2025 Jan 15. doi: 10.1038/s41586-024-08393-x. Online ahead of print. Nature. 2025. PMID: 39814879
Survival with Trastuzumab Emtansine in Residual HER2-Positive Breast Cancer.
Geyer CE Jr, Untch M, Huang CS, Mano MS, Mamounas EP, Wolmark N, Rastogi P, Schneeweiss A, Redondo A, Fischer HH, D'Hondt V, Conlin AK, Guarneri V, Wapnir IL, Jackisch C, Arce-Salinas C, Fasching PA, DiGiovanna MP, Crown JP, Wuelfing P, Shao Z, Rota Caremoli E, Bonnefoi HR, Hennessy BT, Stamatovic L, Castro-Salguero H, Brufsky AM, Knott A, Siddiqui A, Lambertini C, Boulet T, Nyawira B, Restuccia E, Loibl S; KATHERINE Study Group. Geyer CE Jr, et al. N Engl J Med. 2025 Jan 16;392(3):249-257. doi: 10.1056/NEJMoa2406070. N Engl J Med. 2025. PMID: 39813643 Clinical Trial.
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