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Monoclonal IgG antibodies generated from joint-derived B cells of RA patients have a strong bias toward citrullinated autoantigen recognition.
Amara K, Steen J, Murray F, Morbach H, Fernandez-Rodriguez BM, Joshua V, Engström M, Snir O, Israelsson L, Catrina AI, Wardemann H, Corti D, Meffre E, Klareskog L, Malmström V. Amara K, et al. Among authors: snir o. J Exp Med. 2013 Mar 11;210(3):445-55. doi: 10.1084/jem.20121486. Epub 2013 Feb 25. J Exp Med. 2013. Retraction in: J Exp Med. 2019 Jan 7;216(1):245. doi: 10.1084/jem.2012148612112018r PMID: 23440041 Free PMC article. Retracted.
Type II collagen antibody response is enriched in the synovial fluid of rheumatoid joints and directed to the same major epitopes as in collagen induced arthritis in primates and mice.
Lindh I, Snir O, Lönnblom E, Uysal H, Andersson I, Nandakumar KS, Vierboom M, 't Hart B, Malmström V, Holmdahl R. Lindh I, et al. Among authors: snir o. Arthritis Res Ther. 2014 Jul 8;16(4):R143. doi: 10.1186/ar4605. Arthritis Res Ther. 2014. PMID: 25005029 Free PMC article.
74 results