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Role of KATP channels in glucose-regulated glucagon secretion and impaired counterregulation in type 2 diabetes.
Zhang Q, Ramracheya R, Lahmann C, Tarasov A, Bengtsson M, Braha O, Braun M, Brereton M, Collins S, Galvanovskis J, Gonzalez A, Groschner LN, Rorsman NJ, Salehi A, Travers ME, Walker JN, Gloyn AL, Gribble F, Johnson PR, Reimann F, Ashcroft FM, Rorsman P. Zhang Q, et al. Among authors: johnson pr. Cell Metab. 2013 Dec 3;18(6):871-82. doi: 10.1016/j.cmet.2013.10.014. Cell Metab. 2013. PMID: 24315372 Free PMC article.
R-type Ca(2+)-channel-evoked CICR regulates glucose-induced somatostatin secretion.
Zhang Q, Bengtsson M, Partridge C, Salehi A, Braun M, Cox R, Eliasson L, Johnson PR, Renström E, Schneider T, Berggren PO, Göpel S, Ashcroft FM, Rorsman P. Zhang Q, et al. Among authors: johnson pr. Nat Cell Biol. 2007 Apr;9(4):453-60. doi: 10.1038/ncb1563. Epub 2007 Mar 18. Nat Cell Biol. 2007. PMID: 17369816
Adrenaline Stimulates Glucagon Secretion by Tpc2-Dependent Ca2+ Mobilization From Acidic Stores in Pancreatic α-Cells.
Hamilton A, Zhang Q, Salehi A, Willems M, Knudsen JG, Ringgaard AK, Chapman CE, Gonzalez-Alvarez A, Surdo NC, Zaccolo M, Basco D, Johnson PRV, Ramracheya R, Rutter GA, Galione A, Rorsman P, Tarasov AI. Hamilton A, et al. Diabetes. 2018 Jun;67(6):1128-1139. doi: 10.2337/db17-1102. Epub 2018 Mar 21. Diabetes. 2018. PMID: 29563152 Free PMC article.
Reduced insulin exocytosis in human pancreatic β-cells with gene variants linked to type 2 diabetes.
Rosengren AH, Braun M, Mahdi T, Andersson SA, Travers ME, Shigeto M, Zhang E, Almgren P, Ladenvall C, Axelsson AS, Edlund A, Pedersen MG, Jonsson A, Ramracheya R, Tang Y, Walker JN, Barrett A, Johnson PR, Lyssenko V, McCarthy MI, Groop L, Salehi A, Gloyn AL, Renström E, Rorsman P, Eliasson L. Rosengren AH, et al. Among authors: johnson pr. Diabetes. 2012 Jul;61(7):1726-33. doi: 10.2337/db11-1516. Epub 2012 Apr 9. Diabetes. 2012. PMID: 22492527 Free PMC article.
Per-arnt-sim (PAS) domain-containing protein kinase is downregulated in human islets in type 2 diabetes and regulates glucagon secretion.
da Silva Xavier G, Farhan H, Kim H, Caxaria S, Johnson P, Hughes S, Bugliani M, Marselli L, Marchetti P, Birzele F, Sun G, Scharfmann R, Rutter J, Siniakowicz K, Weir G, Parker H, Reimann F, Gribble FM, Rutter GA. da Silva Xavier G, et al. Diabetologia. 2011 Apr;54(4):819-27. doi: 10.1007/s00125-010-2010-7. Epub 2010 Dec 23. Diabetologia. 2011. PMID: 21181396 Free PMC article.
526 results