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Three SARS-CoV-2 spike protein variants delivered intranasally by measles and mumps vaccines are broadly protective.
Zhang Y, Chamblee M, Xu J, Qu P, Shamseldin MM, Yoo SJ, Misny J, Thongpan I, Kc M, Hall JM, Gupta YA, Evans JP, Lu M, Ye C, Hsu CC, Liang X, Martinez-Sobrido L, Yount JS, Boyaka PN, Liu SL, Dubey P, Peeples ME, Li J. Zhang Y, et al. Nat Commun. 2024 Jul 3;15(1):5589. doi: 10.1038/s41467-024-49443-2. Nat Commun. 2024. PMID: 38961063 Free PMC article.
A new tractable method for generating human alveolar macrophage-like cells in vitro to study lung inflammatory processes and diseases.
Pahari S, Arnett E, Simper J, Azad A, Guerrero-Arguero I, Ye C, Zhang H, Cai H, Wang Y, Lai Z, Jarvis N, Lumbreras M, Maselli DJ, Peters J, Torrelles JB, Martinez-Sobrido L, Schlesinger LS. Pahari S, et al. mBio. 2023 Aug 31;14(4):e0083423. doi: 10.1128/mbio.00834-23. Epub 2023 Jun 8. mBio. 2023. PMID: 37288969 Free PMC article.
A next-generation intranasal trivalent MMS vaccine induces durable and broad protection against SARS-CoV-2 variants of concern.
Xu J, Zhang Y, Qu P, Shamseldin MM, Yoo SJ, Misny J, Thongpan I, Kc M, Hall JM, Evans JP, Eltobgy M, Lu M, Ye C, Chamblee M, Liang X, Martinez-Sobrido L, Amer AO, Yount JS, Boyaka PN, Peeples ME, Liu SL, Dubey P, Li J. Xu J, et al. Proc Natl Acad Sci U S A. 2023 Oct 10;120(41):e2220403120. doi: 10.1073/pnas.2220403120. Epub 2023 Oct 5. Proc Natl Acad Sci U S A. 2023. PMID: 37796985 Free PMC article.
SARS-CoV-2 nsp15 endoribonuclease antagonizes dsRNA-induced antiviral signaling.
Otter CJ, Bracci N, Parenti NA, Ye C, Asthana A, Blomqvist EK, Tan LH, Pfannenstiel JJ, Jackson N, Fehr AR, Silverman RH, Burke JM, Cohen NA, Martinez-Sobrido L, Weiss SR. Otter CJ, et al. Proc Natl Acad Sci U S A. 2024 Apr 9;121(15):e2320194121. doi: 10.1073/pnas.2320194121. Epub 2024 Apr 3. Proc Natl Acad Sci U S A. 2024. PMID: 38568967 Free PMC article.
Immunization with Recombinant Accessory Protein-Deficient SARS-CoV-2 Protects against Lethal Challenge and Viral Transmission.
Ye C, Park JG, Chiem K, Dravid P, Allué-Guardia A, Garcia-Vilanova A, Pino Tamayo P, Shivanna V, Kapoor A, Walter MR, Kobie JJ, Plemper RK, Torrelles JB, Martinez-Sobrido L. Ye C, et al. Microbiol Spectr. 2023 Jun 15;11(3):e0065323. doi: 10.1128/spectrum.00653-23. Epub 2023 May 16. Microbiol Spectr. 2023. PMID: 37191507 Free PMC article.
Transmissible SARS-CoV-2 variants with resistance to clinical protease inhibitors.
Moghadasi SA, Heilmann E, Khalil AM, Nnabuife C, Kearns FL, Ye C, Moraes SN, Costacurta F, Esler MA, Aihara H, von Laer D, Martinez-Sobrido L, Palzkill T, Amaro RE, Harris RS. Moghadasi SA, et al. Sci Adv. 2023 Mar 29;9(13):eade8778. doi: 10.1126/sciadv.ade8778. Epub 2023 Mar 29. Sci Adv. 2023. PMID: 36989354 Free PMC article.
312 results