Wills J - Search Results

1

The metabolic fate of [14C]-fenclozic acid in the hepatic reductase null (HRN) mouse.

Pickup K, Wills J, Rodrigues A, Jones HB, Page C, Martin S, Sarda S, Wilson I. Pickup K, et al. Among authors: wills j. Xenobiotica. 2014 Jan;44(2):164-73. doi: 10.3109/00498254.2013.866299. Epub 2013 Dec 10. Xenobiotica. 2014. PMID: 24320884

2

Acute liver effects, disposition and metabolic fate of [¹⁴C]-fenclozic acid following oral administration to normal and bile-cannulated male C57BL/6J mice.

Pickup K, Martin S, Partridge EA, Jones HB, Wills J, Schulz-Utermoehl T, McCarthy A, Rodrigues A, Page C, Ratcliffe K, Sarda S, Wilson ID. Pickup K, et al. Among authors: wills j. Arch Toxicol. 2017 Jul;91(7):2643-2653. doi: 10.1007/s00204-016-1894-5. Epub 2016 Nov 28. Arch Toxicol. 2017. PMID: 27896398 Free PMC article.

3

Benchmark dose analyses of multiple genetic toxicity endpoints permit robust, cross-tissue comparisons of MutaMouse responses to orally delivered benzo[a]pyrene.

Long AS, Wills JW, Krolak D, Guo M, Dertinger SD, Arlt VM, White PA. Long AS, et al. Arch Toxicol. 2018 Feb;92(2):967-982. doi: 10.1007/s00204-017-2099-2. Epub 2017 Nov 24. Arch Toxicol. 2018. PMID: 29177888 Free PMC article.

4

Comprehensive interpretation of in vitro micronucleus test results for 292 chemicals: from hazard identification to risk assessment application.

Kuo B, Beal MA, Wills JW, White PA, Marchetti F, Nong A, Barton-Maclaren TS, Houck K, Yauk CL. Kuo B, et al. Arch Toxicol. 2022 Jul;96(7):2067-2085. doi: 10.1007/s00204-022-03286-2. Epub 2022 Apr 21. Arch Toxicol. 2022. PMID: 35445829 Free PMC article.

5

Inter-laboratory automation of the in vitro micronucleus assay using imaging flow cytometry and deep learning.

Wills JW, Verma JR, Rees BJ, Harte DSG, Haxhiraj Q, Barnes CM, Barnes R, Rodrigues MA, Doan M, Filby A, Hewitt RE, Thornton CA, Cronin JG, Kenny JD, Buckley R, Lynch AM, Carpenter AE, Summers HD, Johnson GE, Rees P. Wills JW, et al. Arch Toxicol. 2021 Sep;95(9):3101-3115. doi: 10.1007/s00204-021-03113-0. Epub 2021 Jul 10. Arch Toxicol. 2021. PMID: 34245348 Free PMC article.

6

Integration of the TGx-28.65 genomic biomarker with the flow cytometry micronucleus test to assess the genotoxicity of disperse orange and 1,2,4-benzenetriol in human TK6 cells.

Buick JK, Williams A, Kuo B, Wills JW, Swartz CD, Recio L, Li HH, Fornace AJ Jr, Aubrecht J, Yauk CL. Buick JK, et al. Among authors: wills jw. Mutat Res. 2017 Dec;806:51-62. doi: 10.1016/j.mrfmmm.2017.09.002. Epub 2017 Sep 13. Mutat Res. 2017. PMID: 29017062

7

Critical review of the current and future challenges associated with advanced in vitro systems towards the study of nanoparticle (secondary) genotoxicity.

Evans SJ, Clift MJ, Singh N, de Oliveira Mallia J, Burgum M, Wills JW, Wilkinson TS, Jenkins GJ, Doak SH. Evans SJ, et al. Among authors: wills jw. Mutagenesis. 2017 Jan;32(1):233-241. doi: 10.1093/mutage/gew054. Epub 2016 Nov 4. Mutagenesis. 2017. PMID: 27815329 Free PMC article. Review.

8

Investigating FlowSight® imaging flow cytometry as a platform to assess chemically induced micronuclei using human lymphoblastoid cells in vitro.

Verma JR, Harte DSG, Shah UK, Summers H, Thornton CA, Doak SH, Jenkins GJS, Rees P, Wills JW, Johnson GE. Verma JR, et al. Among authors: wills jw. Mutagenesis. 2018 Oct 11;33(4):283-289. doi: 10.1093/mutage/gey021. Mutagenesis. 2018. PMID: 30204902

9

Empirical comparison of genotoxic potency estimations: the in vitro DNA-damage ToxTracker endpoints versus the in vivo micronucleus assay.

Wills JW, Halkes-Wellstead E, Summers HD, Rees P, Johnson GE. Wills JW, et al. Mutagenesis. 2021 Aug 27;36(4):311-320. doi: 10.1093/mutage/geab020. Mutagenesis. 2021. PMID: 34111295 Free PMC article.

10

An Analysis of the Practicalities of Multi-Color Nanoparticle Cellular Bar-Coding.

Rees P, Brown MR, Wills JW, Summers H. Rees P, et al. Comb Chem High Throughput Screen. 2016;19(5):362-9. doi: 10.2174/1386207319666160408150649. Comb Chem High Throughput Screen. 2016. PMID: 27055751

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