Alves CH - Search Results

1

Microarray and morphological analysis of early postnatal CRB2 mutant retinas on a pure C57BL/6J genetic background.

Alves CH, Bossers K, Vos RM, Essing AH, Swagemakers S, van der Spek PJ, Verhaagen J, Wijnholds J. Alves CH, et al. PLoS One. 2013 Dec 6;8(12):e82532. doi: 10.1371/journal.pone.0082532. eCollection 2013. PLoS One. 2013. PMID: 24324803 Free PMC article.

2

Targeted ablation of Crb2 in photoreceptor cells induces retinitis pigmentosa.

Alves CH, Pellissier LP, Vos RM, Garcia Garrido M, Sothilingam V, Seide C, Beck SC, Klooster J, Furukawa T, Flannery JG, Verhaagen J, Seeliger MW, Wijnholds J. Alves CH, et al. Hum Mol Genet. 2014 Jul 1;23(13):3384-401. doi: 10.1093/hmg/ddu048. Epub 2014 Feb 2. Hum Mol Genet. 2014. PMID: 24493795 Free article.

3

Gene therapy into photoreceptors and Müller glial cells restores retinal structure and function in CRB1 retinitis pigmentosa mouse models.

Pellissier LP, Quinn PM, Alves CH, Vos RM, Klooster J, Flannery JG, Heimel JA, Wijnholds J. Pellissier LP, et al. Among authors: alves ch. Hum Mol Genet. 2015 Jun 1;24(11):3104-18. doi: 10.1093/hmg/ddv062. Epub 2015 Feb 20. Hum Mol Genet. 2015. PMID: 25701872 Free article.

4

AAV Gene Augmentation Therapy for CRB1-Associated Retinitis Pigmentosa.

Alves CH, Wijnholds J. Alves CH, et al. Methods Mol Biol. 2018;1715:135-151. doi: 10.1007/978-1-4939-7522-8_10. Methods Mol Biol. 2018. PMID: 29188511

5

CRB2 in immature photoreceptors determines the superior-inferior symmetry of the developing retina to maintain retinal structure and function.

Quinn PM, Alves CH, Klooster J, Wijnholds J. Quinn PM, et al. Among authors: alves ch. Hum Mol Genet. 2018 Sep 15;27(18):3137-3153. doi: 10.1093/hmg/ddy194. Hum Mol Genet. 2018. PMID: 29893966

6

Human iPSC-Derived Retinas Recapitulate the Fetal CRB1 CRB2 Complex Formation and Demonstrate that Photoreceptors and Müller Glia Are Targets of AAV5.

Quinn PM, Buck TM, Mulder AA, Ohonin C, Alves CH, Vos RM, Bialecka M, van Herwaarden T, van Dijk EHC, Talib M, Freund C, Mikkers HMM, Hoeben RC, Goumans MJ, Boon CJF, Koster AJ, Chuva de Sousa Lopes SM, Jost CR, Wijnholds J. Quinn PM, et al. Among authors: alves ch. Stem Cell Reports. 2019 May 14;12(5):906-919. doi: 10.1016/j.stemcr.2019.03.002. Epub 2019 Apr 4. Stem Cell Reports. 2019. PMID: 30956116 Free PMC article.

7

CRB2 Loss in Rod Photoreceptors Is Associated with Progressive Loss of Retinal Contrast Sensitivity.

Alves CH, Boon N, Mulder AA, Koster AJ, Jost CR, Wijnholds J. Alves CH, et al. Int J Mol Sci. 2019 Aug 21;20(17):4069. doi: 10.3390/ijms20174069. Int J Mol Sci. 2019. PMID: 31438467 Free PMC article.

8

Defining Phenotype, Tropism, and Retinal Gene Therapy Using Adeno-Associated Viral Vectors (AAVs) in New-Born Brown Norway Rats with a Spontaneous Mutation in Crb1.

Boon N, Alves CH, Mulder AA, Andriessen CA, Buck TM, Quinn PMJ, Vos RM, Koster AJ, Jost CR, Wijnholds J. Boon N, et al. Among authors: alves ch. Int J Mol Sci. 2021 Mar 30;22(7):3563. doi: 10.3390/ijms22073563. Int J Mol Sci. 2021. PMID: 33808129 Free PMC article.

9

Microglial Cell Dysfunction in CRB1-Associated Retinopathies.

Alves CH, Wijnholds J. Alves CH, et al. Adv Exp Med Biol. 2019;1185:159-163. doi: 10.1007/978-3-030-27378-1_26. Adv Exp Med Biol. 2019. PMID: 31884605 Review.

10

AAV-CRB2 protects against vision loss in an inducible CRB1 retinitis pigmentosa mouse model.

Buck TM, Vos RM, Alves CH, Wijnholds J. Buck TM, et al. Among authors: alves ch. Mol Ther Methods Clin Dev. 2020 Dec 25;20:423-441. doi: 10.1016/j.omtm.2020.12.012. eCollection 2021 Mar 12. Mol Ther Methods Clin Dev. 2020. PMID: 33575434 Free PMC article.

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