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Type 2 diabetes and congenital hyperinsulinism cause DNA double-strand breaks and p53 activity in β cells.
Tornovsky-Babeay S, Dadon D, Ziv O, Tzipilevich E, Kadosh T, Schyr-Ben Haroush R, Hija A, Stolovich-Rain M, Furth-Lavi J, Granot Z, Porat S, Philipson LH, Herold KC, Bhatti TR, Stanley C, Ashcroft FM, In't Veld P, Saada A, Magnuson MA, Glaser B, Dor Y. Tornovsky-Babeay S, et al. Among authors: philipson lh. Cell Metab. 2014 Jan 7;19(1):109-21. doi: 10.1016/j.cmet.2013.11.007. Epub 2013 Dec 12. Cell Metab. 2014. PMID: 24332968 Free article.
When BAD is good for beta cells.
Philipson LH, Roe MW. Philipson LH, et al. Cell Metab. 2008 Apr;7(4):280-1. doi: 10.1016/j.cmet.2008.03.009. Cell Metab. 2008. PMID: 18396130 Free article.
The granular chloride channel ClC-3 is permissive for insulin secretion.
Deriy LV, Gomez EA, Jacobson DA, Wang X, Hopson JA, Liu XY, Zhang G, Bindokas VP, Philipson LH, Nelson DJ. Deriy LV, et al. Among authors: philipson lh. Cell Metab. 2009 Oct;10(4):316-23. doi: 10.1016/j.cmet.2009.08.012. Cell Metab. 2009. PMID: 19808024 Free PMC article.
FOXP3 mutations causing early-onset insulin-requiring diabetes but without other features of immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome.
Hwang JL, Park SY, Ye H, Sanyoura M, Pastore AN, Carmody D, Del Gaudio D, Wilson JF, Hanis CL, Liu X, Atzmon G, Glaser B, Philipson LH, Greeley SAW; T2D-Genes Consortium. Hwang JL, et al. Among authors: philipson lh. Pediatr Diabetes. 2018 May;19(3):388-392. doi: 10.1111/pedi.12612. Epub 2017 Nov 29. Pediatr Diabetes. 2018. PMID: 29193502 Free PMC article.
α Cell Function and Gene Expression Are Compromised in Type 1 Diabetes.
Brissova M, Haliyur R, Saunders D, Shrestha S, Dai C, Blodgett DM, Bottino R, Campbell-Thompson M, Aramandla R, Poffenberger G, Lindner J, Pan FC, von Herrath MG, Greiner DL, Shultz LD, Sanyoura M, Philipson LH, Atkinson M, Harlan DM, Levy SE, Prasad N, Stein R, Powers AC. Brissova M, et al. Among authors: philipson lh. Cell Rep. 2018 Mar 6;22(10):2667-2676. doi: 10.1016/j.celrep.2018.02.032. Cell Rep. 2018. PMID: 29514095 Free PMC article.
425 results