Zhang KY - Search Results

1

Assay methods for small ubiquitin-like modifier (SUMO)-SUMO-interacting motif (SIM) interactions in vivo and in vitro using a split-luciferase complementation system.

Hirohama M, Voet AR, Ozawa T, Saitoh H, Nakao Y, Zhang KY, Ito A, Yoshida M. Hirohama M, et al. Among authors: zhang ky. Anal Biochem. 2014 Mar 1;448:92-4. doi: 10.1016/j.ab.2013.12.009. Epub 2013 Dec 11. Anal Biochem. 2014. PMID: 24333278

2

Pharmacophore modelling as a virtual screening tool for the discovery of small molecule protein-protein interaction inhibitors.

Voet A, Zhang KY. Voet A, et al. Among authors: zhang ky. Curr Pharm Des. 2012;18(30):4586-98. doi: 10.2174/138161212802651616. Curr Pharm Des. 2012. PMID: 22650262 Review.

3

Fragment based drug design: from experimental to computational approaches.

Kumar A, Voet A, Zhang KY. Kumar A, et al. Among authors: zhang ky. Curr Med Chem. 2012;19(30):5128-47. doi: 10.2174/092986712803530467. Curr Med Chem. 2012. PMID: 22934764 Review.

4

An integrated fragment based screening approach for the discovery of small molecule modulators of the VWF-GPIbα interaction.

Jose RA, Voet A, Broos K, Jakobi AJ, Bruylants G, Egle B, Zhang KY, De Maeyer M, Deckmyn H, De Borggraeve WM. Jose RA, et al. Among authors: zhang ky. Chem Commun (Camb). 2012 Nov 28;48(92):11349-51. doi: 10.1039/c2cc35269a. Chem Commun (Camb). 2012. PMID: 23072895

5

The discovery of novel human androgen receptor antagonist chemotypes using a combined pharmacophore screening procedure.

Voet A, Helsen C, Zhang KY, Claessens F. Voet A, et al. Among authors: zhang ky. ChemMedChem. 2013 Apr;8(4):644-51. doi: 10.1002/cmdc.201200549. Epub 2013 Feb 21. ChemMedChem. 2013. PMID: 23436650

6

Identification of sumoylation activating enzyme 1 inhibitors by structure-based virtual screening.

Kumar A, Ito A, Hirohama M, Yoshida M, Zhang KY. Kumar A, et al. Among authors: zhang ky. J Chem Inf Model. 2013 Apr 22;53(4):809-20. doi: 10.1021/ci300618e. Epub 2013 Apr 8. J Chem Inf Model. 2013. PMID: 23544417

7

Protein interface pharmacophore mapping tools for small molecule protein: protein interaction inhibitor discovery.

Voet A, Banwell EF, Sahu KK, Heddle JG, Zhang KY. Voet A, et al. Among authors: zhang ky. Curr Top Med Chem. 2013;13(9):989-1001. doi: 10.2174/1568026611313090003. Curr Top Med Chem. 2013. PMID: 23651479 Review.

8

Identification of quinazolinyloxy biaryl urea as a new class of SUMO activating enzyme 1 inhibitors.

Kumar A, Ito A, Hirohama M, Yoshida M, Zhang KY. Kumar A, et al. Among authors: zhang ky. Bioorg Med Chem Lett. 2013 Sep 15;23(18):5145-9. doi: 10.1016/j.bmcl.2013.07.022. Epub 2013 Jul 19. Bioorg Med Chem Lett. 2013. PMID: 23920437

9

Identification of small peptides inhibiting the integrase-LEDGF/p75 interaction through targeting the cellular co-factor.

Cavalluzzo C, Christ F, Voet A, Sharma A, Singh BK, Zhang KY, Lescrinier E, De Maeyer M, Debyser Z, Van der Eycken E. Cavalluzzo C, et al. Among authors: zhang ky. J Pept Sci. 2013 Oct;19(10):651-8. doi: 10.1002/psc.2543. Epub 2013 Aug 27. J Pept Sci. 2013. PMID: 24014475

10

Electrostatic similarities between protein and small molecule ligands facilitate the design of protein-protein interaction inhibitors.

Voet A, Berenger F, Zhang KY. Voet A, et al. Among authors: zhang ky. PLoS One. 2013 Oct 10;8(10):e75762. doi: 10.1371/journal.pone.0075762. eCollection 2013. PLoS One. 2013. PMID: 24130741 Free PMC article.

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