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Peroxisome proliferator-activated receptor γ coactivator 1α regulates mitochondrial calcium homeostasis, sarcoplasmic reticulum stress, and cell death to mitigate skeletal muscle aging.
Gill JF, Delezie J, Santos G, McGuirk S, Schnyder S, Frank S, Rausch M, St-Pierre J, Handschin C. Gill JF, et al. Among authors: handschin c. Aging Cell. 2019 Oct;18(5):e12993. doi: 10.1111/acel.12993. Epub 2019 Jul 10. Aging Cell. 2019. PMID: 31290266 Free PMC article.
The corepressor NCoR1 antagonizes PGC-1α and estrogen-related receptor α in the regulation of skeletal muscle function and oxidative metabolism.
Pérez-Schindler J, Summermatter S, Salatino S, Zorzato F, Beer M, Balwierz PJ, van Nimwegen E, Feige JN, Auwerx J, Handschin C. Pérez-Schindler J, et al. Among authors: handschin c. Mol Cell Biol. 2012 Dec;32(24):4913-24. doi: 10.1128/MCB.00877-12. Epub 2012 Oct 1. Mol Cell Biol. 2012. PMID: 23028049 Free PMC article.
157 results