Lin PJ - Search Results

1

Influence of Polyethylene Glycol Lipid Desorption Rates on Pharmacokinetics and Pharmacodynamics of siRNA Lipid Nanoparticles.

Mui BL, Tam YK, Jayaraman M, Ansell SM, Du X, Tam YY, Lin PJ, Chen S, Narayanannair JK, Rajeev KG, Manoharan M, Akinc A, Maier MA, Cullis P, Madden TD, Hope MJ. Mui BL, et al. Among authors: lin pj. Mol Ther Nucleic Acids. 2013 Dec 17;2(12):e139. doi: 10.1038/mtna.2013.66. Mol Ther Nucleic Acids. 2013. PMID: 24345865 Free PMC article.

2

Lipid nanoparticle siRNA systems for silencing the androgen receptor in human prostate cancer in vivo.

Lee JB, Zhang K, Tam YY, Tam YK, Belliveau NM, Sung VY, Lin PJ, LeBlanc E, Ciufolini MA, Rennie PS, Cullis PR. Lee JB, et al. Among authors: lin pj. Int J Cancer. 2012 Sep 1;131(5):E781-90. doi: 10.1002/ijc.27361. Epub 2012 Jan 3. Int J Cancer. 2012. PMID: 22095615

3

Influence of cationic lipid composition on uptake and intracellular processing of lipid nanoparticle formulations of siRNA.

Lin PJ, Tam YY, Hafez I, Sandhu A, Chen S, Ciufolini MA, Nabi IR, Cullis PR. Lin PJ, et al. Nanomedicine. 2013 Feb;9(2):233-46. doi: 10.1016/j.nano.2012.05.019. Epub 2012 Jun 12. Nanomedicine. 2013. PMID: 22698807

4

Small molecule ligands for enhanced intracellular delivery of lipid nanoparticle formulations of siRNA.

Tam YY, Chen S, Zaifman J, Tam YK, Lin PJ, Ansell S, Roberge M, Ciufolini MA, Cullis PR. Tam YY, et al. Among authors: lin pj. Nanomedicine. 2013 Jul;9(5):665-74. doi: 10.1016/j.nano.2012.11.006. Epub 2012 Dec 6. Nanomedicine. 2013. PMID: 23219877

5

Microfluidic Synthesis of Highly Potent Limit-size Lipid Nanoparticles for In Vivo Delivery of siRNA.

Belliveau NM, Huft J, Lin PJ, Chen S, Leung AK, Leaver TJ, Wild AW, Lee JB, Taylor RJ, Tam YK, Hansen CL, Cullis PR. Belliveau NM, et al. Among authors: lin pj. Mol Ther Nucleic Acids. 2012 Aug 14;1(8):e37. doi: 10.1038/mtna.2012.28. Mol Ther Nucleic Acids. 2012. PMID: 23344179 Free PMC article.

6

Lipid Nanoparticle Delivery of siRNA to Silence Neuronal Gene Expression in the Brain.

Rungta RL, Choi HB, Lin PJ, Ko RW, Ashby D, Nair J, Manoharan M, Cullis PR, Macvicar BA. Rungta RL, et al. Among authors: lin pj. Mol Ther Nucleic Acids. 2013 Dec 3;2(12):e136. doi: 10.1038/mtna.2013.65. Mol Ther Nucleic Acids. 2013. PMID: 24301867 Free PMC article.

7

Microfluidic-based manufacture of siRNA-lipid nanoparticles for therapeutic applications.

Walsh C, Ou K, Belliveau NM, Leaver TJ, Wild AW, Huft J, Lin PJ, Chen S, Leung AK, Lee JB, Hansen CL, Taylor RJ, Ramsay EC, Cullis PR. Walsh C, et al. Among authors: lin pj. Methods Mol Biol. 2014;1141:109-20. doi: 10.1007/978-1-4939-0363-4_6. Methods Mol Biol. 2014. PMID: 24567134

8

Development of lipid nanoparticle formulations of siRNA for hepatocyte gene silencing following subcutaneous administration.

Chen S, Tam YY, Lin PJ, Leung AK, Tam YK, Cullis PR. Chen S, et al. Among authors: lin pj. J Control Release. 2014 Dec 28;196:106-12. doi: 10.1016/j.jconrel.2014.09.025. Epub 2014 Oct 5. J Control Release. 2014. PMID: 25285610

9

The cellular mechanisms of neuronal swelling underlying cytotoxic edema.

Rungta RL, Choi HB, Tyson JR, Malik A, Dissing-Olesen L, Lin PJC, Cain SM, Cullis PR, Snutch TP, MacVicar BA. Rungta RL, et al. Cell. 2015 Apr 23;161(3):610-621. doi: 10.1016/j.cell.2015.03.029. Cell. 2015. PMID: 25910210 Free article.

10

siRNA Lipid Nanoparticle Potently Silences Clusterin and Delays Progression When Combined with Androgen Receptor Cotargeting in Enzalutamide-Resistant Prostate Cancer.

Yamamoto Y, Lin PJ, Beraldi E, Zhang F, Kawai Y, Leong J, Katsumi H, Fazli L, Fraser R, Cullis PR, Gleave M. Yamamoto Y, et al. Among authors: lin pj. Clin Cancer Res. 2015 Nov 1;21(21):4845-55. doi: 10.1158/1078-0432.CCR-15-0866. Epub 2015 Jun 23. Clin Cancer Res. 2015. PMID: 26106075

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