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Experimental genital tract infection demonstrates Neisseria gonorrhoeae MtrCDE efflux pump is not required for in vivo human infection and identifies gonococcal colonization bottleneck.
Waltmann A, Balthazar JT, Begum AA, Hua N, Jerse AE, Shafer WM, Hobbs MM, Duncan JA. Waltmann A, et al. Among authors: begum aa. PLoS Pathog. 2024 Sep 25;20(9):e1012578. doi: 10.1371/journal.ppat.1012578. eCollection 2024 Sep. PLoS Pathog. 2024. PMID: 39321205 Free PMC article. Clinical Trial.
Neisseria gonorrhoeae MtrCDE Efflux Pump During In Vivo Experimental Genital Tract Infection in Men and Mice Reveals the Presence of Within-Host Colonization Bottleneck.
Waltmann A, Balthazar JT, Begum AA, Hua N, Jerse AE, Shafer WM; UNC-Global Clinical Trials Unit/DMID 09-0106 Study Team; Hobbs MM, Duncan JA. Waltmann A, et al. Among authors: begum aa. medRxiv [Preprint]. 2023 Jun 29:2023.06.23.23291824. doi: 10.1101/2023.06.23.23291824. medRxiv. 2023. Update in: PLoS Pathog. 2024 Sep 25;20(9):e1012578. doi: 10.1371/journal.ppat.1012578 PMID: 37425726 Free PMC article. Updated. Preprint.
A Single Amino Acid Substitution in Elongation Factor G Can Confer Low-Level Gentamicin Resistance in Neisseria gonorrhoeae.
Holley CL, Dhulipala V, Balthazar JT, Le Van A, Begum AA, Chen SC, Read TD, Matoga M, Hoffman IF, Golparian D, Unemo M, Jerse AE, Shafer WM. Holley CL, et al. Among authors: begum aa. Antimicrob Agents Chemother. 2022 May 17;66(5):e0025122. doi: 10.1128/aac.00251-22. Epub 2022 Apr 25. Antimicrob Agents Chemother. 2022. PMID: 35465683 Free PMC article.
Peptide-based targeted polymeric nanoparticles for siRNA delivery.
Hussein WM, Cheong YS, Liu C, Liu G, Begum AA, Attallah MA, Moyle PM, Torchilin VP, Smith R, Toth I. Hussein WM, et al. Among authors: begum aa. Nanotechnology. 2019 Oct 11;30(41):415604. doi: 10.1088/1361-6528/ab313d. Epub 2019 Jul 11. Nanotechnology. 2019. PMID: 31295734
35 results