Goetz R - Search Results

1

Parathyroid-specific deletion of Klotho unravels a novel calcineurin-dependent FGF23 signaling pathway that regulates PTH secretion.

Olauson H, Lindberg K, Amin R, Sato T, Jia T, Goetz R, Mohammadi M, Andersson G, Lanske B, Larsson TE. Olauson H, et al. Among authors: goetz r. PLoS Genet. 2013;9(12):e1003975. doi: 10.1371/journal.pgen.1003975. Epub 2013 Dec 12. PLoS Genet. 2013. PMID: 24348262 Free PMC article.

2

Arterial klotho expression and FGF23 effects on vascular calcification and function.

Lindberg K, Olauson H, Amin R, Ponnusamy A, Goetz R, Taylor RF, Mohammadi M, Canfield A, Kublickiene K, Larsson TE. Lindberg K, et al. Among authors: goetz r. PLoS One. 2013;8(4):e60658. doi: 10.1371/journal.pone.0060658. Epub 2013 Apr 5. PLoS One. 2013. PMID: 23577141 Free PMC article.

3

FGF-23-Klotho signaling stimulates proliferation and prevents vitamin D-induced apoptosis.

Medici D, Razzaque MS, Deluca S, Rector TL, Hou B, Kang K, Goetz R, Mohammadi M, Kuro-O M, Olsen BR, Lanske B. Medici D, et al. Among authors: goetz r. J Cell Biol. 2008 Aug 11;182(3):459-65. doi: 10.1083/jcb.200803024. Epub 2008 Aug 4. J Cell Biol. 2008. PMID: 18678710 Free PMC article.

4

In vivo genetic evidence for klotho-dependent, fibroblast growth factor 23 (Fgf23) -mediated regulation of systemic phosphate homeostasis.

Nakatani T, Sarraj B, Ohnishi M, Densmore MJ, Taguchi T, Goetz R, Mohammadi M, Lanske B, Razzaque MS. Nakatani T, et al. Among authors: goetz r. FASEB J. 2009 Feb;23(2):433-41. doi: 10.1096/fj.08-114397. Epub 2008 Oct 3. FASEB J. 2009. PMID: 18835926 Free PMC article.

5

Exploring mechanisms of FGF signalling through the lens of structural biology.

Goetz R, Mohammadi M. Goetz R, et al. Nat Rev Mol Cell Biol. 2013 Mar;14(3):166-80. doi: 10.1038/nrm3528. Epub 2013 Feb 13. Nat Rev Mol Cell Biol. 2013. PMID: 23403721 Free PMC article. Review.

6

Isolated C-terminal tail of FGF23 alleviates hypophosphatemia by inhibiting FGF23-FGFR-Klotho complex formation.

Goetz R, Nakada Y, Hu MC, Kurosu H, Wang L, Nakatani T, Shi M, Eliseenkova AV, Razzaque MS, Moe OW, Kuro-o M, Mohammadi M. Goetz R, et al. Proc Natl Acad Sci U S A. 2010 Jan 5;107(1):407-12. doi: 10.1073/pnas.0902006107. Epub 2009 Dec 4. Proc Natl Acad Sci U S A. 2010. PMID: 19966287 Free PMC article.

7

FGF23 acts directly on renal proximal tubules to induce phosphaturia through activation of the ERK1/2-SGK1 signaling pathway.

Andrukhova O, Zeitz U, Goetz R, Mohammadi M, Lanske B, Erben RG. Andrukhova O, et al. Among authors: goetz r. Bone. 2012 Sep;51(3):621-8. doi: 10.1016/j.bone.2012.05.015. Epub 2012 May 27. Bone. 2012. PMID: 22647968 Free PMC article.

8

FGF23-induced hypophosphatemia persists in Hyp mice deficient in the WNT coreceptor Lrp6.

Uchihashi K, Nakatani T, Goetz R, Mohammadi M, He X, Razzaque MS. Uchihashi K, et al. Among authors: goetz r. Contrib Nephrol. 2013;180:124-37. doi: 10.1159/000346792. Epub 2013 May 3. Contrib Nephrol. 2013. PMID: 23652555 Free PMC article.

9

A G protein-coupled, IP3/protein kinase C pathway controlling the synthesis of phosphaturic hormone FGF23.

He Q, Shumate LT, Matthias J, Aydin C, Wein MN, Spatz JM, Goetz R, Mohammadi M, Plagge A, Divieti Pajevic P, Bastepe M. He Q, et al. Among authors: goetz r. JCI Insight. 2019 Sep 5;4(17):e125007. doi: 10.1172/jci.insight.125007. JCI Insight. 2019. PMID: 31484825 Free PMC article.

10

The parathyroid is a target organ for FGF23 in rats.

Ben-Dov IZ, Galitzer H, Lavi-Moshayoff V, Goetz R, Kuro-o M, Mohammadi M, Sirkis R, Naveh-Many T, Silver J. Ben-Dov IZ, et al. Among authors: goetz r. J Clin Invest. 2007 Dec;117(12):4003-8. doi: 10.1172/JCI32409. J Clin Invest. 2007. PMID: 17992255 Free PMC article.

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