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The perinucleolar compartment associates with malignancy.
Wen Y, Wang C, Huang S. Wen Y, et al. Among authors: wang c. Front Biol (Beijing). 2013 Aug 1;8(4):10.1007/s11515-013-1265-z. doi: 10.1007/s11515-013-1265-z. Front Biol (Beijing). 2013. PMID: 24348523 Free PMC article.
Metarrestin, a perinucleolar compartment inhibitor, effectively suppresses metastasis.
Frankowski KJ, Wang C, Patnaik S, Schoenen FJ, Southall N, Li D, Teper Y, Sun W, Kandela I, Hu D, Dextras C, Knotts Z, Bian Y, Norton J, Titus S, Lewandowska MA, Wen Y, Farley KI, Griner LM, Sultan J, Meng Z, Zhou M, Vilimas T, Powers AS, Kozlov S, Nagashima K, Quadri HS, Fang M, Long C, Khanolkar O, Chen W, Kang J, Huang H, Chow E, Goldberg E, Feldman C, Xi R, Kim HR, Sahagian G, Baserga SJ, Mazar A, Ferrer M, Zheng W, Shilatifard A, Aubé J, Rudloff U, Marugan JJ, Huang S. Frankowski KJ, et al. Among authors: wang c. Sci Transl Med. 2018 May 16;10(441):eaap8307. doi: 10.1126/scitranslmed.aap8307. Sci Transl Med. 2018. PMID: 29769289 Free PMC article.
The perinucleolar compartment is directly associated with DNA.
Norton JT, Wang C, Gjidoda A, Henry RW, Huang S. Norton JT, et al. Among authors: wang c. J Biol Chem. 2009 Feb 13;284(7):4090-101. doi: 10.1074/jbc.M807255200. Epub 2008 Nov 17. J Biol Chem. 2009. PMID: 19015260 Free PMC article.
Nuclear function of Alus.
Wang C, Huang S. Wang C, et al. Nucleus. 2014 Mar-Apr;5(2):131-7. doi: 10.4161/nucl.28005. Epub 2014 Feb 4. Nucleus. 2014. PMID: 24637839 Free PMC article. Review.
Drug Development Against Metastatic Cancers.
Wang C, Huang S. Wang C, et al. Yale J Biol Med. 2017 Mar 29;90(1):119-123. eCollection 2017 Mar. Yale J Biol Med. 2017. PMID: 28356899 Free PMC article. Review.
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