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ASXLs binding to the PHD2/3 fingers of MLL4 provides a mechanism for the recruitment of BAP1 to active enhancers.
Zhang Y, Xie G, Lee JE, Zandian M, Sudarshan D, Estavoyer B, Benz C, Viita T, Asgaritarghi G, Lachance C, Messmer C, Simonetti L, Sinha VK, Lambert JP, Chen YW, Wang SP, Ivarsson Y, Affar EB, Côté J, Ge K, Kutateladze TG. Zhang Y, et al. Among authors: lambert jp. Nat Commun. 2024 Jun 7;15(1):4883. doi: 10.1038/s41467-024-49391-x. Nat Commun. 2024. PMID: 38849395 Free PMC article.
DNA damage remodels the MITF interactome to increase melanoma genomic instability.
Binet R, Lambert JP, Tomkova M, Tischfield S, Baggiolini A, Picaud S, Sarkar S, Louphrasitthiphol P, Dias D, Carreira S, Humphrey TC, Fillipakopoulos P, White R, Goding CR. Binet R, et al. Among authors: lambert jp. Genes Dev. 2024 Feb 13;38(1-2):70-94. doi: 10.1101/gad.350740.123. Genes Dev. 2024. PMID: 38316520 Free PMC article.
The Identification of Nuclear FMRP Isoform Iso6 Partners.
Ledoux N, Lelong EIJ, Simard A, Hussein S, Adjibade P, Lambert JP, Mazroui R. Ledoux N, et al. Among authors: lambert jp. Cells. 2023 Dec 9;12(24):2807. doi: 10.3390/cells12242807. Cells. 2023. PMID: 38132127 Free PMC article.
Acetylation reprograms MITF target selectivity and residence time.
Louphrasitthiphol P, Loffreda A, Pogenberg V, Picaud S, Schepsky A, Friedrichsen H, Zeng Z, Lashgari A, Thomas B, Patton EE, Wilmanns M, Filippakopoulos P, Lambert JP, Steingrímsson E, Mazza D, Goding CR. Louphrasitthiphol P, et al. Among authors: lambert jp. Nat Commun. 2023 Sep 28;14(1):6051. doi: 10.1038/s41467-023-41793-7. Nat Commun. 2023. PMID: 37770430 Free PMC article.
DNA damage-induced interaction between a lineage addiction oncogenic transcription factor and the MRN complex shapes a tissue-specific DNA Damage Response and cancer predisposition.
Binet R, Lambert JP, Tomkova M, Tischfield S, Baggiolini A, Picaud S, Sarkar S, Louphrasitthiphol P, Dias D, Carreira S, Humphrey T, Fillipakopoulos P, White R, Goding CR. Binet R, et al. Among authors: lambert jp. bioRxiv [Preprint]. 2023 Apr 21:2023.04.21.537819. doi: 10.1101/2023.04.21.537819. bioRxiv. 2023. PMID: 37131595 Free PMC article. Preprint.
Isocitrate dehydrogenase 1 sustains a hybrid cytoplasmic-mitochondrial tricarboxylic acid cycle that can be targeted for therapeutic purposes in prostate cancer.
Gonthier K, Weidmann C, Berthiaume L, Jobin C, Lacouture A, Lafront C, Harvey M, Neveu B, Loehr J, Bergeron A, Fradet Y, Lacombe L, Riopel J, Latulippe É, Atallah C, Shum M, Lambert JP, Pouliot F, Pelletier M, Audet-Walsh É. Gonthier K, et al. Among authors: lambert jp. Mol Oncol. 2023 Oct;17(10):2109-2125. doi: 10.1002/1878-0261.13441. Epub 2023 Jul 19. Mol Oncol. 2023. PMID: 37086156 Free PMC article.
Multilevel interrogation of H3.3 reveals a primordial role in transcription regulation.
Nabeel-Shah S, Garg J, Ashraf K, Jeyapala R, Lee H, Petrova A, Burns JD, Pu S, Zhang Z, Greenblatt JF, Pearlman RE, Lambert JP, Fillingham J. Nabeel-Shah S, et al. Among authors: lambert jp. Epigenetics Chromatin. 2023 Apr 7;16(1):10. doi: 10.1186/s13072-023-00484-9. Epigenetics Chromatin. 2023. PMID: 37024975 Free PMC article.
154 results