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Preclinical characterization of Aurora kinase inhibitor R763/AS703569 identified through an image-based phenotypic screen.
McLaughlin J, Markovtsov V, Li H, Wong S, Gelman M, Zhu Y, Franci C, Lang D, Pali E, Lasaga J, Low C, Zhao F, Chang B, Gururaja TL, Xu W, Baluom M, Sweeny D, Carroll D, Sran A, Thota S, Parmer M, Romane A, Clemens G, Grossbard E, Qu K, Jenkins Y, Kinoshita T, Taylor V, Holland SJ, Argade A, Singh R, Pine P, Payan DG, Hitoshi Y. McLaughlin J, et al. Among authors: li h. J Cancer Res Clin Oncol. 2010 Jan;136(1):99-113. doi: 10.1007/s00432-009-0641-1. J Cancer Res Clin Oncol. 2010. PMID: 19609559
Design, synthesis of diaminopyrimidine inhibitors targeting IgE- and IgG-mediated activation of Fc receptor signaling.
Argade A, Bhamidipati S, Li H, Sylvain C, Clough J, Carroll D, Keim H, Braselmann S, Taylor V, Zhao H, Herlaar E, Issakani SD, Wong BR, Masuda ES, Payan DG, Singh R. Argade A, et al. Among authors: li h. Bioorg Med Chem Lett. 2015;25(10):2122-8. doi: 10.1016/j.bmcl.2015.03.072. Epub 2015 Apr 1. Bioorg Med Chem Lett. 2015. PMID: 25891105
Bicyclic pyrimidine compounds as potent IRAK4 inhibitors.
Chen Y, Tso K, Heckrodt TJ, Li H, Yen R, Lin N, Singh R, Taylor V, Masuda ES, Park G, Payan DG. Chen Y, et al. Among authors: li h. Bioorg Med Chem Lett. 2022 Oct 1;73:128900. doi: 10.1016/j.bmcl.2022.128900. Epub 2022 Jul 18. Bioorg Med Chem Lett. 2022. PMID: 35863718
Application of cultured human mast cells (CHMC) for the design and structure-activity relationship of IgE-mediated mast cell activation inhibitors.
Argade A, Bhamidipati S, Li H, Carroll D, Clough J, Keim H, Sylvain C, Rossi AB, Coquilla C, Issakani SD, Masuda ES, Payan DG, Singh R. Argade A, et al. Among authors: li h. Bioorg Med Chem Lett. 2015;25(10):2117-21. doi: 10.1016/j.bmcl.2015.03.075. Epub 2015 Mar 31. Bioorg Med Chem Lett. 2015. PMID: 25872982
Discovery of a novel class of targeted kinase inhibitors that blocks protein kinase C signaling and ameliorates retinal vascular leakage in a diabetic rat model.
Grant S, Tran P, Zhang Q, Zou A, Dinh D, Jensen J, Zhou S, Kang X, Zachwieja J, Lippincott J, Liu K, Johnson SL, Scales S, Yin C, Nukui S, Stoner C, Prasanna G, Lafontaine J, Wells P, Li H. Grant S, et al. Among authors: li h. Eur J Pharmacol. 2010 Feb 10;627(1-3):16-25. doi: 10.1016/j.ejphar.2009.10.029. Epub 2009 Oct 20. Eur J Pharmacol. 2010. PMID: 19850035
Antibiotic susceptibility testing and molecular characterization based on whole-genome sequencing of Streptococcus pneumoniae isolates from pediatric infections at the National Regional Medical Center of Southwest China during the COVID-19 pandemic.
Yan Z, Miao C, Liu L, Fu Y, Liu X, Li H, Kuang L, Cui Y, Jiang Y. Yan Z, et al. Among authors: li h. Front Public Health. 2024 Dec 10;12:1490401. doi: 10.3389/fpubh.2024.1490401. eCollection 2024. Front Public Health. 2024. PMID: 39720806 Free PMC article.
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