Treinies I - Search Results

1

Potent, selective small molecule inhibitors of type III phosphatidylinositol-4-kinase α- but not β-inhibit the phosphatidylinositol signaling cascade and cancer cell proliferation.

Waring MJ, Andrews DM, Faulder PF, Flemington V, McKelvie JC, Maman S, Preston M, Raubo P, Robb GR, Roberts K, Rowlinson R, Smith JM, Swarbrick ME, Treinies I, Winter JJ, Wood RJ. Waring MJ, et al. Among authors: treinies i. Chem Commun (Camb). 2014 May 25;50(40):5388-90. doi: 10.1039/c3cc48391f. Epub 2013 Dec 24. Chem Commun (Camb). 2014. PMID: 24366037

2

Identification and optimization of a novel series of selective PIP5K inhibitors.

Andrews DM, Cartic S, Cosulich S, Divecha N, Faulder P, Flemington V, Kern O, Kettle JG, MacDonald E, McKelvie J, Pike KG, Roberts B, Rowlinson R, Smith JM, Stockley M, Swarbrick ME, Treinies I, Waring MJ. Andrews DM, et al. Among authors: treinies i. Bioorg Med Chem. 2022 Jan 15;54:116557. doi: 10.1016/j.bmc.2021.116557. Epub 2021 Dec 12. Bioorg Med Chem. 2022. PMID: 34922306

3

Activated MEK stimulates expression of AP-1 components independently of phosphatidylinositol 3-kinase (PI3-kinase) but requires a PI3-kinase signal To stimulate DNA synthesis.

Treinies I, Paterson HF, Hooper S, Wilson R, Marshall CJ. Treinies I, et al. Mol Cell Biol. 1999 Jan;19(1):321-9. doi: 10.1128/MCB.19.1.321. Mol Cell Biol. 1999. PMID: 9858556 Free PMC article.

4

Fibroblast growth factor-21 improves pancreatic beta-cell function and survival by activation of extracellular signal-regulated kinase 1/2 and Akt signaling pathways.

Wente W, Efanov AM, Brenner M, Kharitonenkov A, Köster A, Sandusky GE, Sewing S, Treinies I, Zitzer H, Gromada J. Wente W, et al. Among authors: treinies i. Diabetes. 2006 Sep;55(9):2470-8. doi: 10.2337/db05-1435. Diabetes. 2006. PMID: 16936195

5

The PDZ/coiled-coil domain containing protein PIST modulates insulin secretion in MIN6 insulinoma cells by interacting with somatostatin receptor subtype 5.

Wente W, Efanov AM, Treinies I, Zitzer H, Gromada J, Richter D, Kreienkamp HJ. Wente W, et al. Among authors: treinies i. FEBS Lett. 2005 Nov 21;579(28):6305-10. doi: 10.1016/j.febslet.2005.10.009. Epub 2005 Oct 21. FEBS Lett. 2005. PMID: 16263117 Free article.

6

Inhibition of recombinant K(ATP) channels by the antidiabetic agents midaglizole, LY397364 and LY389382.

Proks P, Treinies I, Mest HJ, Trapp S. Proks P, et al. Among authors: treinies i. Eur J Pharmacol. 2002 Sep 27;452(1):11-9. doi: 10.1016/s0014-2999(02)02234-3. Eur J Pharmacol. 2002. PMID: 12323381

7

Glucose-induced insulin secretion is potentiated by a new imidazoline compound.

Mest HJ, Raap A, Schloos J, Treinies I, Paal M, Giese U, Koivisto V. Mest HJ, et al. Among authors: treinies i. Naunyn Schmiedebergs Arch Pharmacol. 2001 Jul;364(1):47-52. doi: 10.1007/s002100100415. Naunyn Schmiedebergs Arch Pharmacol. 2001. PMID: 11485038

8

Development of transforming function during transduction of proto-ras into Harvey sarcoma virus.

Lang M, Treinies I, Duesberg PH, Kurth R, Cichutek K. Lang M, et al. Among authors: treinies i. Proc Natl Acad Sci U S A. 1994 Jan 18;91(2):654-8. doi: 10.1073/pnas.91.2.654. Proc Natl Acad Sci U S A. 1994. PMID: 8290577 Free PMC article.

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