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Targeting the cytosolic innate immune receptors RIG-I and MDA5 effectively counteracts cancer cell heterogeneity in glioblastoma.
Glas M, Coch C, Trageser D, Dassler J, Simon M, Koch P, Mertens J, Quandel T, Gorris R, Reinartz R, Wieland A, Von Lehe M, Pusch A, Roy K, Schlee M, Neumann H, Fimmers R, Herrlinger U, Brüstle O, Hartmann G, Besch R, Scheffler B. Glas M, et al. Among authors: mertens j. Stem Cells. 2013 Jun;31(6):1064-74. doi: 10.1002/stem.1350. Stem Cells. 2013. PMID: 23390110
Directly Reprogrammed Human Neurons Retain Aging-Associated Transcriptomic Signatures and Reveal Age-Related Nucleocytoplasmic Defects.
Mertens J, Paquola ACM, Ku M, Hatch E, Böhnke L, Ladjevardi S, McGrath S, Campbell B, Lee H, Herdy JR, Gonçalves JT, Toda T, Kim Y, Winkler J, Yao J, Hetzer MW, Gage FH. Mertens J, et al. Cell Stem Cell. 2015 Dec 3;17(6):705-718. doi: 10.1016/j.stem.2015.09.001. Epub 2015 Oct 8. Cell Stem Cell. 2015. PMID: 26456686 Free PMC article.
Generation of functional human serotonergic neurons from fibroblasts.
Vadodaria KC, Mertens J, Paquola A, Bardy C, Li X, Jappelli R, Fung L, Marchetto MC, Hamm M, Gorris M, Koch P, Gage FH. Vadodaria KC, et al. Among authors: mertens j. Mol Psychiatry. 2016 Jan;21(1):49-61. doi: 10.1038/mp.2015.161. Epub 2015 Oct 27. Mol Psychiatry. 2016. PMID: 26503761
The different moods of human serotonergic neurons.
Vadodaria KC, Mertens J, Paquola A, Bardy C, Li X, Jappelli R, Fung L, Marchetto MC, Hamm M, Gorris M, Koch P, Gage FH. Vadodaria KC, et al. Among authors: mertens j. Mol Psychiatry. 2016 Jan;21(1):3. doi: 10.1038/mp.2015.202. Mol Psychiatry. 2016. PMID: 26678308 No abstract available.
582 results