DeFranco AL - Search Results

1

Requirement for MyD88 signaling in B cells and dendritic cells for germinal center anti-nuclear antibody production in Lyn-deficient mice.

Hua Z, Gross AJ, Lamagna C, Ramos-Hernández N, Scapini P, Ji M, Shao H, Lowell CA, Hou B, DeFranco AL. Hua Z, et al. Among authors: defranco al. J Immunol. 2014 Feb 1;192(3):875-85. doi: 10.4049/jimmunol.1300683. Epub 2013 Dec 30. J Immunol. 2014. PMID: 24379120 Free PMC article.

2

B cell-specific loss of Lyn kinase leads to autoimmunity.

Lamagna C, Hu Y, DeFranco AL, Lowell CA. Lamagna C, et al. Among authors: defranco al. J Immunol. 2014 Feb 1;192(3):919-28. doi: 10.4049/jimmunol.1301979. Epub 2013 Dec 27. J Immunol. 2014. PMID: 24376269 Free PMC article.

3

B Cell-Intrinsic MyD88 Signaling Promotes Initial Cell Proliferation and Differentiation To Enhance the Germinal Center Response to a Virus-like Particle.

Tian M, Hua Z, Hong S, Zhang Z, Liu C, Lin L, Chen J, Zhang W, Zhou X, Zhang F, DeFranco AL, Hou B. Tian M, et al. Among authors: defranco al. J Immunol. 2018 Feb 1;200(3):937-948. doi: 10.4049/jimmunol.1701067. Epub 2017 Dec 27. J Immunol. 2018. PMID: 29282308

4

Developmental acquisition of the Lyn-CD22-SHP-1 inhibitory pathway promotes B cell tolerance.

Gross AJ, Lyandres JR, Panigrahi AK, Prak ET, DeFranco AL. Gross AJ, et al. Among authors: defranco al. J Immunol. 2009 May 1;182(9):5382-92. doi: 10.4049/jimmunol.0803941. J Immunol. 2009. PMID: 19380785 Free PMC article.

5

Selective utilization of Toll-like receptor and MyD88 signaling in B cells for enhancement of the antiviral germinal center response.

Hou B, Saudan P, Ott G, Wheeler ML, Ji M, Kuzmich L, Lee LM, Coffman RL, Bachmann MF, DeFranco AL. Hou B, et al. Among authors: defranco al. Immunity. 2011 Mar 25;34(3):375-84. doi: 10.1016/j.immuni.2011.01.011. Epub 2011 Feb 25. Immunity. 2011. PMID: 21353603 Free PMC article.

6

B cell-derived IL-10 suppresses inflammatory disease in Lyn-deficient mice.

Scapini P, Lamagna C, Hu Y, Lee K, Tang Q, DeFranco AL, Lowell CA. Scapini P, et al. Among authors: defranco al. Proc Natl Acad Sci U S A. 2011 Oct 11;108(41):E823-32. doi: 10.1073/pnas.1107913108. Epub 2011 Sep 12. Proc Natl Acad Sci U S A. 2011. PMID: 21911371 Free PMC article.

7

Elevated BCR signaling and decreased survival of Lyn-deficient transitional and follicular B cells.

Gross AJ, Proekt I, DeFranco AL. Gross AJ, et al. Among authors: defranco al. Eur J Immunol. 2011 Dec;41(12):3645-55. doi: 10.1002/eji.201141708. Epub 2011 Nov 10. Eur J Immunol. 2011. PMID: 21928281 Free PMC article.

8

Lyn deficiency affects B-cell maturation as well as survival.

Shahaf G, Gross AJ, Sternberg-Simon M, Kaplan D, DeFranco AL, Mehr R. Shahaf G, et al. Among authors: defranco al. Eur J Immunol. 2012 Feb;42(2):511-21. doi: 10.1002/eji.201141940. Epub 2011 Dec 14. Eur J Immunol. 2012. PMID: 22057631 Free PMC article.

9

Contribution of Toll-like receptor signaling to germinal center antibody responses.

DeFranco AL, Rookhuizen DC, Hou B. DeFranco AL, et al. Immunol Rev. 2012 May;247(1):64-72. doi: 10.1111/j.1600-065X.2012.01115.x. Immunol Rev. 2012. PMID: 22500832 Free PMC article. Review.

10

Hyperactivated MyD88 signaling in dendritic cells, through specific deletion of Lyn kinase, causes severe autoimmunity and inflammation.

Lamagna C, Scapini P, van Ziffle JA, DeFranco AL, Lowell CA. Lamagna C, et al. Among authors: defranco al. Proc Natl Acad Sci U S A. 2013 Aug 27;110(35):E3311-20. doi: 10.1073/pnas.1300617110. Epub 2013 Aug 12. Proc Natl Acad Sci U S A. 2013. PMID: 23940344 Free PMC article.

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