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Page 1
The NOX toolbox: validating the role of NADPH oxidases in physiology and disease.
Altenhöfer S, Kleikers PW, Radermacher KA, Scheurer P, Rob Hermans JJ, Schiffers P, Ho H, Wingler K, Schmidt HH. Altenhöfer S, et al. Among authors: kleikers pw. Cell Mol Life Sci. 2012 Jul;69(14):2327-43. doi: 10.1007/s00018-012-1010-9. Epub 2012 May 31. Cell Mol Life Sci. 2012. PMID: 22648375 Free PMC article. Review.
The 1027th target candidate in stroke: Will NADPH oxidase hold up?
Radermacher KA, Wingler K, Kleikers P, Altenhöfer S, Jr Hermans J, Kleinschnitz C, Hhw Schmidt H. Radermacher KA, et al. Exp Transl Stroke Med. 2012 May 24;4(1):11. doi: 10.1186/2040-7378-4-11. Exp Transl Stroke Med. 2012. PMID: 22625431 Free PMC article.
Neuroprotection after stroke by targeting NOX4 as a source of oxidative stress.
Radermacher KA, Wingler K, Langhauser F, Altenhöfer S, Kleikers P, Hermans JJ, Hrabě de Angelis M, Kleinschnitz C, Schmidt HH. Radermacher KA, et al. Antioxid Redox Signal. 2013 Apr 20;18(12):1418-27. doi: 10.1089/ars.2012.4797. Epub 2012 Oct 16. Antioxid Redox Signal. 2013. PMID: 22937798 Free PMC article. Review.
VAS2870 is a pan-NADPH oxidase inhibitor.
Wingler K, Altenhoefer SA, Kleikers PW, Radermacher KA, Kleinschnitz C, Schmidt HH. Wingler K, et al. Among authors: kleikers pw. Cell Mol Life Sci. 2012 Sep;69(18):3159-60. doi: 10.1007/s00018-012-1107-1. Epub 2012 Aug 9. Cell Mol Life Sci. 2012. PMID: 22875281 Free PMC article. No abstract available.
NOX4-dependent neuronal autotoxicity and BBB breakdown explain the superior sensitivity of the brain to ischemic damage.
Casas AI, Geuss E, Kleikers PWM, Mencl S, Herrmann AM, Buendia I, Egea J, Meuth SG, Lopez MG, Kleinschnitz C, Schmidt HHHW. Casas AI, et al. Among authors: kleikers pwm. Proc Natl Acad Sci U S A. 2017 Nov 14;114(46):12315-12320. doi: 10.1073/pnas.1705034114. Epub 2017 Oct 31. Proc Natl Acad Sci U S A. 2017. PMID: 29087944 Free PMC article.
NOX5-induced uncoupling of endothelial NO synthase is a causal mechanism and theragnostic target of an age-related hypertension endotype.
Elbatreek MH, Sadegh S, Anastasi E, Guney E, Nogales C, Kacprowski T, Hassan AA, Teubner A, Huang PH, Hsu CY, Schiffers PMH, Janssen GM, Kleikers PWM, Wipat A, Baumbach J, De Mey JGR, Schmidt HHHW. Elbatreek MH, et al. Among authors: kleikers pwm. PLoS Biol. 2020 Nov 10;18(11):e3000885. doi: 10.1371/journal.pbio.3000885. eCollection 2020 Nov. PLoS Biol. 2020. PMID: 33170835 Free PMC article.
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