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An in-depth comparison of latent HIV-1 reactivation in multiple cell model systems and resting CD4+ T cells from aviremic patients.
Spina CA, Anderson J, Archin NM, Bosque A, Chan J, Famiglietti M, Greene WC, Kashuba A, Lewin SR, Margolis DM, Mau M, Ruelas D, Saleh S, Shirakawa K, Siliciano RF, Singhania A, Soto PC, Terry VH, Verdin E, Woelk C, Wooden S, Xing S, Planelles V. Spina CA, et al. PLoS Pathog. 2013;9(12):e1003834. doi: 10.1371/journal.ppat.1003834. Epub 2013 Dec 26. PLoS Pathog. 2013. PMID: 24385908 Free PMC article.
Transcriptomic Analysis Implicates the p53 Signaling Pathway in the Establishment of HIV-1 Latency in Central Memory CD4 T Cells in an In Vitro Model.
White CH, Moesker B, Beliakova-Bethell N, Martins LJ, Spina CA, Margolis DM, Richman DD, Planelles V, Bosque A, Woelk CH. White CH, et al. Among authors: spina ca. PLoS Pathog. 2016 Nov 29;12(11):e1006026. doi: 10.1371/journal.ppat.1006026. eCollection 2016 Nov. PLoS Pathog. 2016. PMID: 27898737 Free PMC article.
Sulfonation pathway inhibitors block reactivation of latent HIV-1.
Murry JP, Godoy J, Mukim A, Swann J, Bruce JW, Ahlquist P, Bosque A, Planelles V, Spina CA, Young JA. Murry JP, et al. Among authors: spina ca. Virology. 2014 Dec;471-473:1-12. doi: 10.1016/j.virol.2014.08.016. Epub 2014 Oct 11. Virology. 2014. PMID: 25310595 Free PMC article.
Mixed effects of suberoylanilide hydroxamic acid (SAHA) on the host transcriptome and proteome and their implications for HIV reactivation from latency.
White CH, Johnston HE, Moesker B, Manousopoulou A, Margolis DM, Richman DD, Spina CA, Garbis SD, Woelk CH, Beliakova-Bethell N. White CH, et al. Among authors: spina ca. Antiviral Res. 2015 Nov;123:78-85. doi: 10.1016/j.antiviral.2015.09.002. Epub 2015 Sep 4. Antiviral Res. 2015. PMID: 26343910 Free PMC article.
Long non-coding RNAs and latent HIV - A search for novel targets for latency reversal.
Trypsteen W, White CH, Mukim A, Spina CA, De Spiegelaere W, Lefever S, Planelles V, Bosque A, Woelk CH, Vandekerckhove L, Beliakova-Bethell N. Trypsteen W, et al. Among authors: spina ca. PLoS One. 2019 Nov 11;14(11):e0224879. doi: 10.1371/journal.pone.0224879. eCollection 2019. PLoS One. 2019. PMID: 31710657 Free PMC article.
CD44 microbeads accelerate HIV-1 infection in T cells.
Terry VH, Johnston IC, Spina CA. Terry VH, et al. Among authors: spina ca. Virology. 2009 Jun 5;388(2):294-304. doi: 10.1016/j.virol.2009.03.022. Epub 2009 Apr 23. Virology. 2009. PMID: 19394995 Free PMC article.
78 results