Xing S - Search Results

1

An in-depth comparison of latent HIV-1 reactivation in multiple cell model systems and resting CD4+ T cells from aviremic patients.

Spina CA, Anderson J, Archin NM, Bosque A, Chan J, Famiglietti M, Greene WC, Kashuba A, Lewin SR, Margolis DM, Mau M, Ruelas D, Saleh S, Shirakawa K, Siliciano RF, Singhania A, Soto PC, Terry VH, Verdin E, Woelk C, Wooden S, Xing S, Planelles V. Spina CA, et al. Among authors: xing s. PLoS Pathog. 2013;9(12):e1003834. doi: 10.1371/journal.ppat.1003834. Epub 2013 Dec 26. PLoS Pathog. 2013. PMID: 24385908 Free PMC article.

2

Targeting HIV latency: pharmacologic strategies toward eradication.

Xing S, Siliciano RF. Xing S, et al. Drug Discov Today. 2013 Jun;18(11-12):541-51. doi: 10.1016/j.drudis.2012.12.008. Epub 2012 Dec 25. Drug Discov Today. 2013. PMID: 23270785 Free PMC article. Review.

3

Unique characteristics of histone deacetylase inhibitors in reactivation of latent HIV-1 in Bcl-2-transduced primary resting CD4+ T cells.

Shan L, Xing S, Yang HC, Zhang H, Margolick JB, Siliciano RF. Shan L, et al. Among authors: xing s. J Antimicrob Chemother. 2014 Jan;69(1):28-33. doi: 10.1093/jac/dkt338. Epub 2013 Sep 1. J Antimicrob Chemother. 2014. PMID: 23999005 Free PMC article.

4

Small-molecule screening using a human primary cell model of HIV latency identifies compounds that reverse latency without cellular activation.

Yang HC, Xing S, Shan L, O'Connell K, Dinoso J, Shen A, Zhou Y, Shrum CK, Han Y, Liu JO, Zhang H, Margolick JB, Siliciano RF. Yang HC, et al. Among authors: xing s. J Clin Invest. 2009 Nov;119(11):3473-86. doi: 10.1172/JCI39199. Epub 2009 Oct 1. J Clin Invest. 2009. PMID: 19805909 Free PMC article.

5

Disulfiram reactivates latent HIV-1 in a Bcl-2-transduced primary CD4+ T cell model without inducing global T cell activation.

Xing S, Bullen CK, Shroff NS, Shan L, Yang HC, Manucci JL, Bhat S, Zhang H, Margolick JB, Quinn TC, Margolis DM, Siliciano JD, Siliciano RF. Xing S, et al. J Virol. 2011 Jun;85(12):6060-4. doi: 10.1128/JVI.02033-10. Epub 2011 Apr 6. J Virol. 2011. PMID: 21471244 Free PMC article.

6

Novel structurally related compounds reactivate latent HIV-1 in a bcl-2-transduced primary CD4+ T cell model without inducing global T cell activation.

Xing S, Bhat S, Shroff NS, Zhang H, Lopez JA, Margolick JB, Liu JO, Siliciano RF. Xing S, et al. J Antimicrob Chemother. 2012 Feb;67(2):398-403. doi: 10.1093/jac/dkr496. Epub 2011 Dec 7. J Antimicrob Chemother. 2012. PMID: 22160146 Free PMC article.

7

BET bromodomain-targeting compounds reactivate HIV from latency via a Tat-independent mechanism.

Boehm D, Calvanese V, Dar RD, Xing S, Schroeder S, Martins L, Aull K, Li PC, Planelles V, Bradner JE, Zhou MM, Siliciano RF, Weinberger L, Verdin E, Ott M. Boehm D, et al. Among authors: xing s. Cell Cycle. 2013 Feb 1;12(3):452-62. doi: 10.4161/cc.23309. Epub 2012 Feb 1. Cell Cycle. 2013. PMID: 23255218 Free PMC article.

8

A critical subset model provides a conceptual basis for the high antiviral activity of major HIV drugs.

Shen L, Rabi SA, Sedaghat AR, Shan L, Lai J, Xing S, Siliciano RF. Shen L, et al. Among authors: xing s. Sci Transl Med. 2011 Jul 13;3(91):91ra63. doi: 10.1126/scitranslmed.3002304. Sci Transl Med. 2011. PMID: 21753122 Free PMC article.

9

Transcriptional Reprogramming during Effector-to-Memory Transition Renders CD4⁺ T Cells Permissive for Latent HIV-1 Infection.

Shan L, Deng K, Gao H, Xing S, Capoferri AA, Durand CM, Rabi SA, Laird GM, Kim M, Hosmane NN, Yang HC, Zhang H, Margolick JB, Li L, Cai W, Ke R, Flavell RA, Siliciano JD, Siliciano RF. Shan L, et al. Among authors: xing s. Immunity. 2017 Oct 17;47(4):766-775.e3. doi: 10.1016/j.immuni.2017.09.014. Immunity. 2017. PMID: 29045905 Free PMC article.

10

The HBV drug entecavir - effects on HIV-1 replication and resistance.

McMahon MA, Jilek BL, Brennan TP, Shen L, Zhou Y, Wind-Rotolo M, Xing S, Bhat S, Hale B, Hegarty R, Chong CR, Liu JO, Siliciano RF, Thio CL. McMahon MA, et al. Among authors: xing s. N Engl J Med. 2007 Jun 21;356(25):2614-21. doi: 10.1056/NEJMoa067710. N Engl J Med. 2007. PMID: 17582071 Free PMC article.

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