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Endocannabinoid and cannabinoid-like fatty acid amide levels correlate with pain-related symptoms in patients with IBS-D and IBS-C: a pilot study.
Fichna J, Wood JT, Papanastasiou M, Vadivel SK, Oprocha P, Sałaga M, Sobczak M, Mokrowiecka A, Cygankiewicz AI, Zakrzewski PK, Małecka-Panas E, Krajewska WM, Kościelniak P, Makriyannis A, Storr MA. Fichna J, et al. PLoS One. 2013 Dec 27;8(12):e85073. doi: 10.1371/journal.pone.0085073. eCollection 2013. PLoS One. 2013. PMID: 24386448 Free PMC article. Clinical Trial.
Activation of the endogenous nociceptin system by selective nociceptin receptor agonist SCH 221510 produces antitransit and antinociceptive effect: a novel strategy for treatment of diarrhea-predominant IBS.
Fichna J, Sobczak M, Mokrowiecka A, Cygankiewicz AI, Zakrzewski PK, Cenac N, Sałaga M, Timmermans JP, Vergnolle N, Małecka-Panas E, Krajewska WM, Storr M. Fichna J, et al. Neurogastroenterol Motil. 2014 Nov;26(11):1539-50. doi: 10.1111/nmo.12390. Epub 2014 Jul 15. Neurogastroenterol Motil. 2014. PMID: 25041572
FABP4 blocker attenuates colonic hypomotility and modulates white adipose tissue-derived hormone levels in mouse models mimicking constipation-predominant IBS.
Mosińska P, Jacenik D, Sałaga M, Wasilewski A, Cygankiewicz A, Sibaev A, Mokrowiecka A, Małecka-Panas E, Pintelon I, Storr M, Timmermans JP, Krajewska WM, Fichna J. Mosińska P, et al. Neurogastroenterol Motil. 2018 May;30(5):e13272. doi: 10.1111/nmo.13272. Epub 2017 Dec 20. Neurogastroenterol Motil. 2018. PMID: 29266569
205 results