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Page 1
Structural basis of PI(4,5)P2-dependent regulation of GluA1 by phosphatidylinositol-5-phosphate 4-kinase, type II, alpha (PIP5K2A).
Seebohm G, Wrobel E, Pusch M, Dicks M, Terhag J, Matschke V, Rothenberg I, Ursu ON, Hertel F, Pott L, Lang F, Schulze-Bahr E, Hollmann M, Stoll R, Strutz-Seebohm N. Seebohm G, et al. Among authors: rothenberg i. Pflugers Arch. 2014 Oct;466(10):1885-97. doi: 10.1007/s00424-013-1424-8. Epub 2014 Jan 5. Pflugers Arch. 2014. PMID: 24389605 Free PMC article.
KCNE1 induces fenestration in the Kv7.1/KCNE1 channel complex that allows for highly specific pharmacological targeting.
Wrobel E, Rothenberg I, Krisp C, Hundt F, Fraenzel B, Eckey K, Linders JT, Gallacher DJ, Towart R, Pott L, Pusch M, Yang T, Roden DM, Kurata HT, Schulze-Bahr E, Strutz-Seebohm N, Wolters D, Seebohm G. Wrobel E, et al. Among authors: rothenberg i. Nat Commun. 2016 Oct 12;7:12795. doi: 10.1038/ncomms12795. Nat Commun. 2016. PMID: 27731317 Free PMC article.
Structural interplay of KV7.1 and KCNE1 is essential for normal repolarization and is compromised in short QT syndrome 2 (KV7.1-A287T).
Rothenberg I, Piccini I, Wrobel E, Stallmeyer B, Müller J, Greber B, Strutz-Seebohm N, Schulze-Bahr E, Schmitt N, Seebohm G. Rothenberg I, et al. HeartRhythm Case Rep. 2016 Sep 12;2(6):521-529. doi: 10.1016/j.hrcr.2016.08.015. eCollection 2016 Nov. HeartRhythm Case Rep. 2016. PMID: 28491751 Free PMC article. No abstract available.
Precision medicine and metabolic syndrome.
Gharipour M, Nezafati P, Sadeghian L, Eftekhari A, Rothenberg I, Jahanfar S. Gharipour M, et al. Among authors: rothenberg i. ARYA Atheroscler. 2022 Jul;18(4):1-10. doi: 10.22122/arya.2022.26215. ARYA Atheroscler. 2022. PMID: 36817343 Free PMC article. Review.
11 results