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Germ-line JAK2 mutations in the kinase domain are responsible for hereditary thrombocytosis and are resistant to JAK2 and HSP90 inhibitors.
Marty C, Saint-Martin C, Pecquet C, Grosjean S, Saliba J, Mouton C, Leroy E, Harutyunyan AS, Abgrall JF, Favier R, Toussaint A, Solary E, Kralovics R, Constantinescu SN, Najman A, Vainchenker W, Plo I, Bellanné-Chantelot C. Marty C, et al. Among authors: constantinescu sn. Blood. 2014 Feb 27;123(9):1372-83. doi: 10.1182/blood-2013-05-504555. Epub 2014 Jan 7. Blood. 2014. PMID: 24398328 Free article.
Microarray analysis of LIF/Stat3 transcriptional targets in embryonic stem cells.
Sekkaï D, Gruel G, Herry M, Moucadel V, Constantinescu SN, Albagli O, Tronik-Le Roux D, Vainchenker W, Bennaceur-Griscelli A. Sekkaï D, et al. Among authors: constantinescu sn. Stem Cells. 2005 Nov-Dec;23(10):1634-42. doi: 10.1634/stemcells.2005-0182. Epub 2005 Aug 11. Stem Cells. 2005. PMID: 16099994
Role of tyrosine kinases and phosphatases in polycythemia vera.
Zhao ZJ, Vainchenker W, Krantz SB, Casadevall N, Constantinescu SN. Zhao ZJ, et al. Among authors: constantinescu sn. Semin Hematol. 2005 Oct;42(4):221-9. doi: 10.1053/j.seminhematol.2005.05.019. Semin Hematol. 2005. PMID: 16210035 Review.
JAK2, the JAK2 V617F mutant and cytokine receptors.
Staerk J, Kallin A, Royer Y, Diaconu CC, Dusa A, Demoulin JB, Vainchenker W, Constantinescu SN. Staerk J, et al. Among authors: constantinescu sn. Pathol Biol (Paris). 2007 Mar;55(2):88-91. doi: 10.1016/j.patbio.2006.06.003. Epub 2006 Aug 14. Pathol Biol (Paris). 2007. PMID: 16904848 Review.
220 results