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Design, synthesis and biological evaluation of 3,5-disubstituted 2-amino thiophene derivatives as a novel class of antitumor agents.
Romagnoli R, Baraldi PG, Lopez-Cara C, Salvador MK, Preti D, Tabrizi MA, Balzarini J, Nussbaumer P, Bassetto M, Brancale A, Fu XH, Yang-Gao, Li J, Zhang SZ, Hamel E, Bortolozzi R, Basso G, Viola G. Romagnoli R, et al. Among authors: fu xh. Bioorg Med Chem. 2014 Sep 15;22(18):5097-109. doi: 10.1016/j.bmc.2013.12.030. Epub 2013 Dec 24. Bioorg Med Chem. 2014. PMID: 24398384 Free PMC article.
One-pot synthesis and biological evaluation of 2-pyrrolidinyl-4-amino-5-(3',4',5'-trimethoxybenzoyl)thiazole: a unique, highly active antimicrotubule agent.
Romagnoli R, Baraldi PG, Lopez Cara C, Kimatrai Salvador M, Bortolozzi R, Basso G, Viola G, Balzarini J, Brancale A, Fu XH, Li J, Zhang SZ, Hamel E. Romagnoli R, et al. Among authors: fu xh. Eur J Med Chem. 2011 Dec;46(12):6015-24. doi: 10.1016/j.ejmech.2011.10.013. Epub 2011 Oct 15. Eur J Med Chem. 2011. PMID: 22027100 Free PMC article.
Synthesis and evaluation of 1,5-disubstituted tetrazoles as rigid analogues of combretastatin A-4 with potent antiproliferative and antitumor activity.
Romagnoli R, Baraldi PG, Salvador MK, Preti D, Aghazadeh Tabrizi M, Brancale A, Fu XH, Li J, Zhang SZ, Hamel E, Bortolozzi R, Basso G, Viola G. Romagnoli R, et al. Among authors: fu xh. J Med Chem. 2012 Jan 12;55(1):475-88. doi: 10.1021/jm2013979. Epub 2011 Dec 21. J Med Chem. 2012. PMID: 22136312 Free PMC article.
Concise synthesis and biological evaluation of 2-Aroyl-5-amino benzo[b]thiophene derivatives as a novel class of potent antimitotic agents.
Romagnoli R, Baraldi PG, Lopez-Cara C, Preti D, Aghazadeh Tabrizi M, Balzarini J, Bassetto M, Brancale A, Fu XH, Gao Y, Li J, Zhang SZ, Hamel E, Bortolozzi R, Basso G, Viola G. Romagnoli R, et al. Among authors: fu xh. J Med Chem. 2013 Nov 27;56(22):9296-309. doi: 10.1021/jm4013938. Epub 2013 Nov 11. J Med Chem. 2013. PMID: 24164557 Free PMC article.
232 results