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The human liver fatty acid binding protein (FABP1) gene is activated by FOXA1 and PPARα; and repressed by C/EBPα: Implications in FABP1 down-regulation in nonalcoholic fatty liver disease.
Guzmán C, Benet M, Pisonero-Vaquero S, Moya M, García-Mediavilla MV, Martínez-Chantar ML, González-Gallego J, Castell JV, Sánchez-Campos S, Jover R. Guzmán C, et al. Among authors: jover r. Biochim Biophys Acta. 2013 Apr;1831(4):803-18. doi: 10.1016/j.bbalip.2012.12.014. Epub 2013 Jan 12. Biochim Biophys Acta. 2013. PMID: 23318274
CCAAT/enhancer-binding protein alpha (C/EBPalpha) and hepatocyte nuclear factor 4alpha (HNF4alpha) synergistically cooperate with constitutive androstane receptor to transactivate the human cytochrome P450 2B6 (CYP2B6) gene: application to the development of a metabolically competent human hepatic cell model.
Benet M, Lahoz A, Guzmán C, Castell JV, Jover R. Benet M, et al. Among authors: jover r. J Biol Chem. 2010 Sep 10;285(37):28457-71. doi: 10.1074/jbc.M110.118364. Epub 2010 Jul 9. J Biol Chem. 2010. PMID: 20622021 Free PMC article.
Transcriptional activation of CYP2C9, CYP1A1, and CYP1A2 by hepatocyte nuclear factor 4alpha requires coactivators peroxisomal proliferator activated receptor-gamma coactivator 1alpha and steroid receptor coactivator 1.
Martínez-Jiménez CP, Castell JV, Gómez-Lechón MJ, Jover R. Martínez-Jiménez CP, et al. Among authors: jover r. Mol Pharmacol. 2006 Nov;70(5):1681-92. doi: 10.1124/mol.106.025403. Epub 2006 Aug 1. Mol Pharmacol. 2006. PMID: 16882880
355 results