Newton DL - Search Results

1

Oxyphenisatin acetate (NSC 59687) triggers a cell starvation response leading to autophagy, mitochondrial dysfunction, and autocrine TNFα-mediated apoptosis.

Morrison BL, Mullendore ME, Stockwin LH, Borgel S, Hollingshead MG, Newton DL. Morrison BL, et al. Among authors: newton dl. Cancer Med. 2013 Oct;2(5):687-700. doi: 10.1002/cam4.107. Epub 2013 Jul 23. Cancer Med. 2013. PMID: 24403234 Free PMC article.

2

ARC (NSC 188491) has identical activity to Sangivamycin (NSC 65346) including inhibition of both P-TEFb and PKC.

Stockwin LH, Yu SX, Stotler H, Hollingshead MG, Newton DL. Stockwin LH, et al. Among authors: newton dl. BMC Cancer. 2009 Feb 20;9:63. doi: 10.1186/1471-2407-9-63. BMC Cancer. 2009. PMID: 19232100 Free PMC article.

3

Sodium dichloroacetate selectively targets cells with defects in the mitochondrial ETC.

Stockwin LH, Yu SX, Borgel S, Hancock C, Wolfe TL, Phillips LR, Hollingshead MG, Newton DL. Stockwin LH, et al. Among authors: newton dl. Int J Cancer. 2010 Dec 1;127(11):2510-9. doi: 10.1002/ijc.25499. Int J Cancer. 2010. PMID: 20533281

4

A copper chelate of thiosemicarbazone NSC 689534 induces oxidative/ER stress and inhibits tumor growth in vitro and in vivo.

Hancock CN, Stockwin LH, Han B, Divelbiss RD, Jun JH, Malhotra SV, Hollingshead MG, Newton DL. Hancock CN, et al. Among authors: newton dl. Free Radic Biol Med. 2011 Jan 1;50(1):110-21. doi: 10.1016/j.freeradbiomed.2010.10.696. Epub 2010 Nov 4. Free Radic Biol Med. 2011. PMID: 20971185 Free PMC article.

5

The "survivin suppressants" NSC 80467 and YM155 induce a DNA damage response.

Glaros TG, Stockwin LH, Mullendore ME, Smith B, Morrison BL, Newton DL. Glaros TG, et al. Among authors: newton dl. Cancer Chemother Pharmacol. 2012 Jul;70(1):207-12. doi: 10.1007/s00280-012-1868-0. Epub 2012 Apr 21. Cancer Chemother Pharmacol. 2012. PMID: 22526412

6

Gene expression profiling of 49 human tumor xenografts from in vitro culture through multiple in vivo passages--strategies for data mining in support of therapeutic studies.

Hollingshead MG, Stockwin LH, Alcoser SY, Newton DL, Orsburn BC, Bonomi CA, Borgel SD, Divelbiss R, Dougherty KM, Hager EJ, Holbeck SL, Kaur G, Kimmel DJ, Kunkel MW, Millione A, Mullendore ME, Stotler H, Collins J. Hollingshead MG, et al. Among authors: newton dl. BMC Genomics. 2014 May 22;15(1):393. doi: 10.1186/1471-2164-15-393. BMC Genomics. 2014. PMID: 24885658 Free PMC article.

7

"Vasocrine" formation of tumor cell-lined vascular spaces: implications for rational design of antiangiogenic therapies.

Rybak SM, Sanovich E, Hollingshead MG, Borgel SD, Newton DL, Melillo G, Kong D, Kaur G, Sausville EA. Rybak SM, et al. Among authors: newton dl. Cancer Res. 2003 Jun 1;63(11):2812-9. Cancer Res. 2003. PMID: 12782586

8

Proteomic analysis identifies oxidative stress induction by adaphostin.

Stockwin LH, Bumke MA, Yu SX, Webb SP, Collins JR, Hollingshead MG, Newton DL. Stockwin LH, et al. Among authors: newton dl. Clin Cancer Res. 2007 Jun 15;13(12):3667-81. doi: 10.1158/1078-0432.CCR-07-0025. Clin Cancer Res. 2007. PMID: 17575232

9

Artemisinin dimer anticancer activity correlates with heme-catalyzed reactive oxygen species generation and endoplasmic reticulum stress induction.

Stockwin LH, Han B, Yu SX, Hollingshead MG, ElSohly MA, Gul W, Slade D, Galal AM, Newton DL, Bumke MA. Stockwin LH, et al. Among authors: newton dl. Int J Cancer. 2009 Sep 15;125(6):1266-75. doi: 10.1002/ijc.24496. Int J Cancer. 2009. PMID: 19533749 Free PMC article.

10

Proteomic analysis of nuclei isolated from cancer cell lines treated with indenoisoquinoline NSC 724998, a novel topoisomerase I inhibitor.

Han B, Stockwin LH, Hancock C, Yu SX, Hollingshead MG, Newton DL. Han B, et al. Among authors: newton dl. J Proteome Res. 2010 Aug 6;9(8):4016-27. doi: 10.1021/pr100194d. J Proteome Res. 2010. PMID: 20515076 Free PMC article.

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