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Hypermethylation of the alternative AWT1 promoter in hematological malignancies is a highly specific marker for acute myeloid leukemias despite high expression levels.
Guillaumet-Adkins A, Richter J, Odero MD, Sandoval J, Agirre X, Catala A, Esteller M, Prósper F, Calasanz MJ, Buño I, Kwon M, Court F, Siebert R, Monk D. Guillaumet-Adkins A, et al. Among authors: calasanz mj. J Hematol Oncol. 2014 Jan 9;7:4. doi: 10.1186/1756-8722-7-4. J Hematol Oncol. 2014. PMID: 24405639 Free PMC article.
Molecular characterization of a t(1;3)(p36;q21) in a patient with MDS. MEL1 is widely expressed in normal tissues, including bone marrow, and it is not overexpressed in the t(1;3) cells.
Lahortiga I, Agirre X, Belloni E, Vázquez I, Larrayoz MJ, Gasparini P, Lo Coco F, Pelicci PG, Calasanz MJ, Odero MD. Lahortiga I, et al. Among authors: calasanz mj. Oncogene. 2004 Jan 8;23(1):311-6. doi: 10.1038/sj.onc.1206923. Oncogene. 2004. PMID: 14712237 Free article.
245 results