Exploiting subsite S1 of trypsin-like serine proteases for selectivity: potent and selective inhibitors of urokinase-type plasminogen activator.
Mackman RL, Katz BA, Breitenbucher JG, Hui HC, Verner E, Luong C, Liu L, Sprengeler PA.
Mackman RL, et al. Among authors: hui hc.
J Med Chem. 2001 Nov 8;44(23):3856-71. doi: 10.1021/jm010244+.
J Med Chem. 2001.
PMID: 11689072
.; Spencer, J.; Allen, D.; Hataye, J.; Hruzewicz, W.; Hui, H. C.; Kolesnikov, A.; Li, Y.; Luong, C.; Martelli, A.; Radika. K.; Rai, R.; She, M.; Shrader, W.; Sprengeler, P. ...The water molecule, H(2)O1(S1), in both the Ser190 or Ala190 enzymes, hydrogen bond …
.; Spencer, J.; Allen, D.; Hataye, J.; Hruzewicz, W.; Hui, H. C.; Kolesnikov, A.; Li, Y.; Luong, C.; Martelli, A.; Radika. K.; …