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IFN-γ-mediated reduction of large-conductance, Ca2+-activated, voltage-dependent K+ (BK) channel activity in airway epithelial cells leads to mucociliary dysfunction.
Manzanares D, Srinivasan M, Salathe ST, Ivonnet P, Baumlin N, Dennis JS, Conner GE, Salathe M. Manzanares D, et al. Among authors: salathe st. Am J Physiol Lung Cell Mol Physiol. 2014 Mar 1;306(5):L453-62. doi: 10.1152/ajplung.00247.2013. Epub 2014 Jan 10. Am J Physiol Lung Cell Mol Physiol. 2014. PMID: 24414257 Free PMC article.