Willmore E - Search Results

1

Identification of dual DNA-PK MDR1 inhibitors for the potentiation of cytotoxic drug activity.

Mould E, Berry P, Jamieson D, Hill C, Cano C, Tan N, Elliott S, Durkacz B, Newell D, Willmore E. Mould E, et al. Among authors: willmore e. Biochem Pharmacol. 2014 Mar 1;88(1):58-65. doi: 10.1016/j.bcp.2014.01.001. Epub 2014 Jan 10. Biochem Pharmacol. 2014. PMID: 24418411

2

Cytotoxic mechanisms of 5-fluoropyrimidines. Relationships with poly(ADP-ribose) polymerase activity, DNA strand breakage and incorporation into nucleic acids.

Willmore E, Durkacz BW. Willmore E, et al. Biochem Pharmacol. 1993 Jul 20;46(2):205-11. doi: 10.1016/0006-2952(93)90405-l. Biochem Pharmacol. 1993. PMID: 8347142

3

A novel DNA-dependent protein kinase inhibitor, NU7026, potentiates the cytotoxicity of topoisomerase II poisons used in the treatment of leukemia.

Willmore E, de Caux S, Sunter NJ, Tilby MJ, Jackson GH, Austin CA, Durkacz BW. Willmore E, et al. Blood. 2004 Jun 15;103(12):4659-65. doi: 10.1182/blood-2003-07-2527. Epub 2004 Mar 9. Blood. 2004. PMID: 15010369 Free article.

4

DNA-dependent protein kinase is a therapeutic target and an indicator of poor prognosis in B-cell chronic lymphocytic leukemia.

Willmore E, Elliott SL, Mainou-Fowler T, Summerfield GP, Jackson GH, O'Neill F, Lowe C, Carter A, Harris R, Pettitt AR, Cano-Soumillac C, Griffin RJ, Cowell IG, Austin CA, Durkacz BW. Willmore E, et al. Clin Cancer Res. 2008 Jun 15;14(12):3984-92. doi: 10.1158/1078-0432.CCR-07-5158. Clin Cancer Res. 2008. PMID: 18559621

5

Mitoxantrone in combination with an inhibitor of DNA-dependent protein kinase: a potential therapy for high risk B-cell chronic lymphocytic leukaemia.

Elliott SL, Crawford C, Mulligan E, Summerfield G, Newton P, Wallis J, Mainou-Fowler T, Evans P, Bedwell C, Durkacz BW, Willmore E. Elliott SL, et al. Among authors: willmore e. Br J Haematol. 2011 Jan;152(1):61-71. doi: 10.1111/j.1365-2141.2010.08425.x. Epub 2010 Nov 18. Br J Haematol. 2011. PMID: 21083655 Free article.

6

The effects of 5-fluoropyrimidines on nascent DNA synthesis in Chinese hamster ovary cells monitored by pH-step alkaline and neutral elution.

Jones S, Willmore E, Durkacz BW. Jones S, et al. Among authors: willmore e. Carcinogenesis. 1994 Nov;15(11):2435-8. doi: 10.1093/carcin/15.11.2435. Carcinogenesis. 1994. PMID: 7955087

7

Selenite induces topoisomerase I and II-DNA complexes in K562 leukemia cells.

López-Lázaro M, Willmore E, Elliott SL, Austin CA. López-Lázaro M, et al. Among authors: willmore e. Int J Cancer. 2008 Nov 1;123(9):2217-21. doi: 10.1002/ijc.23783. Int J Cancer. 2008. PMID: 18712718

8

Selective DNA-PKcs inhibition extends the therapeutic index of localized radiotherapy and chemotherapy.

Willoughby CE, Jiang Y, Thomas HD, Willmore E, Kyle S, Wittner A, Phillips N, Zhao Y, Tudhope SJ, Prendergast L, Junge G, Lourenco LM, Finlay MRV, Turner P, Munck JM, Griffin RJ, Rennison T, Pickles J, Cano C, Newell DR, Reeves HL, Ryan AJ, Wedge SR. Willoughby CE, et al. Among authors: willmore e. J Clin Invest. 2020 Jan 2;130(1):258-271. doi: 10.1172/JCI127483. J Clin Invest. 2020. PMID: 31581151 Free PMC article.

9

Correlation of enhanced 6-mercaptopurine cytotoxicity with increased phosphoribosylpyrophosphate levels in Chinese hamster ovary cells treated with 3-aminobenzamide.

Moses K, Willmore E, Harris AL, Durkacz BW. Moses K, et al. Among authors: willmore e. Cancer Res. 1990 Apr 1;50(7):1992-6. Cancer Res. 1990. PMID: 1690594

10

NF-κB mediates radio-sensitization by the PARP-1 inhibitor, AG-014699.

Hunter JE, Willmore E, Irving JA, Hostomsky Z, Veuger SJ, Durkacz BW. Hunter JE, et al. Among authors: willmore e. Oncogene. 2012 Jan 12;31(2):251-64. doi: 10.1038/onc.2011.229. Epub 2011 Jun 27. Oncogene. 2012. PMID: 21706052 Free PMC article.

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