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Discovery of molecular pathways mediating 1,25-dihydroxyvitamin D3 protection against cytokine-induced inflammation and damage of human and male mouse islets of Langerhans.
Wolden-Kirk H, Rondas D, Bugliani M, Korf H, Van Lommel L, Brusgaard K, Christesen HT, Schuit F, Proost P, Masini M, Marchetti P, Eizirik DL, Overbergh L, Mathieu C. Wolden-Kirk H, et al. Among authors: marchetti p. Endocrinology. 2014 Mar;155(3):736-47. doi: 10.1210/en.2013-1409. Epub 2014 Jan 1. Endocrinology. 2014. PMID: 24424042 Free article.
Th2 cytokines have a partial, direct protective effect on the function and survival of isolated human islets exposed to combined proinflammatory and Th1 cytokines.
Marselli L, Dotta F, Piro S, Santangelo C, Masini M, Lupi R, Realacci M, del Guerra S, Mosca F, Boggi U, Purrello F, Navalesi R, Marchetti P. Marselli L, et al. Among authors: marchetti p. J Clin Endocrinol Metab. 2001 Oct;86(10):4974-8. doi: 10.1210/jcem.86.10.7938. J Clin Endocrinol Metab. 2001. PMID: 11600573
Prolonged exposure to free fatty acids has cytostatic and pro-apoptotic effects on human pancreatic islets: evidence that beta-cell death is caspase mediated, partially dependent on ceramide pathway, and Bcl-2 regulated.
Lupi R, Dotta F, Marselli L, Del Guerra S, Masini M, Santangelo C, Patané G, Boggi U, Piro S, Anello M, Bergamini E, Mosca F, Di Mario U, Del Prato S, Marchetti P. Lupi R, et al. Among authors: marchetti p. Diabetes. 2002 May;51(5):1437-42. doi: 10.2337/diabetes.51.5.1437. Diabetes. 2002. PMID: 11978640
Rosiglitazone prevents the impairment of human islet function induced by fatty acids: evidence for a role of PPARgamma2 in the modulation of insulin secretion.
Lupi R, Del Guerra S, Marselli L, Bugliani M, Boggi U, Mosca F, Marchetti P, Del Prato S. Lupi R, et al. Among authors: marchetti p. Am J Physiol Endocrinol Metab. 2004 Apr;286(4):E560-7. doi: 10.1152/ajpendo.00561.2002. Epub 2003 Nov 18. Am J Physiol Endocrinol Metab. 2004. PMID: 14625208 Free article.
An alternative and simple method to consistently prepare viable isolated human islets for clinical transplantation.
Bugliani M, Lupi R, Del Guerra S, Boggi U, Marselli L, Sbrana S, Vistoli F, Torri S, Del Chiaro M, Signori S, Filipponi F, Del Prato S, Campa M, Corsini V, Campatelli A, Di Candio F, Mosca F, Marchetti P. Bugliani M, et al. Among authors: marchetti p. Transplant Proc. 2004 Apr;36(3):605-6. doi: 10.1016/j.transproceed.2004.02.047. Transplant Proc. 2004. PMID: 15110608
1,468 results