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Inhibition of protein SUMOylation by davidiin, an ellagitannin from Davidia involucrata.
Takemoto M, Kawamura Y, Hirohama M, Yamaguchi Y, Handa H, Saitoh H, Nakao Y, Kawada M, Khalid K, Koshino H, Kimura K, Ito A, Yoshida M. Takemoto M, et al. Among authors: hirohama m. J Antibiot (Tokyo). 2014 Apr;67(4):335-8. doi: 10.1038/ja.2013.142. Epub 2014 Jan 15. J Antibiot (Tokyo). 2014. PMID: 24424345 No abstract available.
Inhibition of protein SUMOylation by natural quinones.
Fukuda I, Hirohama M, Ito A, Tariq M, Igarashi Y, Saitoh H, Yoshida M. Fukuda I, et al. Among authors: hirohama m. J Antibiot (Tokyo). 2016 Oct;69(10):776-779. doi: 10.1038/ja.2016.23. Epub 2016 Mar 9. J Antibiot (Tokyo). 2016. PMID: 26956790 No abstract available.
Spectomycin B1 as a novel SUMOylation inhibitor that directly binds to SUMO E2.
Hirohama M, Kumar A, Fukuda I, Matsuoka S, Igarashi Y, Saitoh H, Takagi M, Shin-ya K, Honda K, Kondoh Y, Saito T, Nakao Y, Osada H, Zhang KY, Yoshida M, Ito A. Hirohama M, et al. ACS Chem Biol. 2013 Dec 20;8(12):2635-42. doi: 10.1021/cb400630z. Epub 2013 Oct 21. ACS Chem Biol. 2013. PMID: 24143955
3CL Protease Inhibitors with an Electrophilic Arylketone Moiety as Anti-SARS-CoV-2 Agents.
Konno S, Kobayashi K, Senda M, Funai Y, Seki Y, Tamai I, Schäkel L, Sakata K, Pillaiyar T, Taguchi A, Taniguchi A, Gütschow M, Müller CE, Takeuchi K, Hirohama M, Kawaguchi A, Kojima M, Senda T, Shirasaka Y, Kamitani W, Hayashi Y. Konno S, et al. Among authors: hirohama m. J Med Chem. 2022 Feb 24;65(4):2926-2939. doi: 10.1021/acs.jmedchem.1c00665. Epub 2021 Jul 27. J Med Chem. 2022. PMID: 34313428
Potent mouse monoclonal antibodies that block SARS-CoV-2 infection.
Guo Y, Kawaguchi A, Takeshita M, Sekiya T, Hirohama M, Yamashita A, Siomi H, Murano K. Guo Y, et al. Among authors: hirohama m. J Biol Chem. 2021 Jan-Jun;296:100346. doi: 10.1016/j.jbc.2021.100346. Epub 2021 Jan 30. J Biol Chem. 2021. PMID: 33524396 Free PMC article.
16 results